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Palbico 100mg Tablet

Salt Composition: PALBOCICLIB

₹3713.00₹18562.50

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Palbico 100mg Tablet

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Palbociclib 100mg is a targeted anticancer therapy belonging to the cyclin-dependent kinase inhibitor class. It is indicated for hormone receptor-positive, human epidermal growth factor 2 negative advanced or metastatic breast cancer, used in combination with other anticancer medications. The medication works by addressing the abnormal uncontrolled multiplication of cancer cells.

Common adverse effects include nausea, vomiting, diarrhoea, fatigue, alopecia, dry skin, rash, infections, epistaxis, decreased appetite, neutropenia and other low blood cell counts, oedema of lips and mouth, dysgeusia, dry eye, blurred vision, and increased lacrimation. Inform your doctor if any side effects persist or cause concern.

Before starting treatment, inform your healthcare provider of any allergies to palbociclib or its components. Disclose any existing conditions including signs of infection (fever, chills, sore throat), liver dysfunction, kidney dysfunction, or sugar intolerance. Report immediately to your physician if you develop dry cough, chest pain, or difficulty breathing, as these may indicate pulmonary inflammation. Provide a complete list of all current medications, including supplements and herbal preparations, prior to initiating therapy.

Effective contraception is essential during treatment and for at least three weeks after the final dose. This medication is not recommended for patients under 18 years of age.

Uses

Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.

How it works

Palbico 100mg Tablet works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.

How to Use

Take the Palbico 100mg Tablet exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this capsule as a whole with a glass of water. Avoid crushing, breaking, or chewing the capsule.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious: Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising) Lung inflammation (chest pain, dry cough, or difficulty breathing) Common: Tiredness Hair loss Dry skin, rash Infections Low blood cell counts. Decreased of appetite Nausea, vomiting

Expert Tips

Avoid consuming grapefruit, grapefruit juice, and products containing St. John’s wort during treatment. Use effective birth control during treatment and for at least 3 weeks after the final dose (females) and 14 weeks after the final dose (males). This medicine may affect fertility. Discuss with your doctor if you have any fertility-related concerns before starting treatment. Your doctor may advise regular blood tests to monitor how the medicine is affecting your blood cells.

References

  1. Pfizer Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 26 Nov 2022], https://www.medicines.org.uk/emc/files/pil.4449.pdf
  2. Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
  3. Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
  4. Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029

Safety Advice

Pregnancy: Unsafe It is not recommended to take Palbico 100mg Tablet during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.

Lungs: Consult Your Doctor You need to tell your physician if you have any lung disorders before taking Palbico 100mg Tablet, as this medication should be used with caution in kidney disorder patients.

Breastfeeding: Consult Your Doctor It is not recommended to take Palbico 100mg Tablet while breastfeeding as it is not known whether it passes into the breast milk. consult your healthcare provider before taking this capsule.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS