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Palbinas 125mg Capsule

Salt Composition: PALBOCICLIB

₹4875.00₹6093.75

Inclusive of all taxes

Palbinas 125mg Capsule

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Palbinas 125 mg is a targeted therapy containing the active constituent palbociclib. It belongs to the group of anticancer medications known as cyclin-dependent kinase inhibitors. It is used in treating hormone receptor-positive, human epidermal growth factor 2 negative advanced or metastatic breast cancer in patients with disease that has spread to other parts of the body. It is given in combination with certain other anticancer medications.

Common side effects associated with Palbinas 125 mg capsule include nausea, vomiting, diarrhoea, tiredness, hair loss, dry skin, rash, infections, nose bleed, decreased appetite, low blood cell counts, swelling of lips and mouth, changes in taste, dry eye, blurred vision, and increased tearing. Inform your doctor if any of these side effects occur or persist.

Inform your healthcare provider if you are allergic to Palbinas 125 mg capsule or its ingredients. Before taking this medicine, it is important to inform your doctor if you have any signs of infections (fever, chills, or sore throat), liver disorders, kidney disorders, or intolerance to some sugars. Consult your physician immediately if you experience symptoms such as dry cough, chest pain, or difficulty breathing, as these could indicate lung inflammation. Inform your physician of all medicines, including supplements and herbal medicines, that you are taking before you start treatment with this medication. Use effective birth control during the treatment and for at least three weeks after the last dose. This medicine is not recommended for patients under 18 years of age.

Uses

Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.

How it works

Palbinas 125 mg capsule works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.

How to Use

Take Palbinas 125 mg capsule exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this capsule as a whole with a glass of water. Avoid crushing, breaking, or chewing the capsule.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious: Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising) Lung inflammation (chest pain, dry cough, or difficulty breathing) Common: Tiredness Hair loss Dry skin, rash Infections Low blood cell counts Decreased of appetite Nausea, vomiting Diarrhea Swelling of lips and mouth Changes in taste Nose bleed Dry eye, blurred vision, increased tearing

Expert Tips

During Palbinas 125 mg capsule treatment, it is advised to avoid grapefruit and its juices and preparations containing St. John's wort. It is recommended to use effective birth control while receiving treatment as well as for at least three weeks after the final dose for females and at least fourteen weeks after the final dose for males. This medication may reduce fertility, so discuss with the physician if you have any concerns. Your doctor may recommend regular blood tests to determine whether Palbinas 125 mg capsule affects your blood cells.

References

  1. Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
  2. Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/

Safety Advice

Pregnancy: unsafe It is not recommended to take Palbinas 125 mg capsule during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.

Lungs: Consult your doctor It is not unknown whether Palbinas 125 mg can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe It is not recommended to take Palbinas 125 mg capsule while breastfeeding as it is not known whether it passes into the breast milk.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS