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Palbo 125mg Capsule

Salt Composition: PALBOCICLIB

₹4882.00₹5742.19

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Palbo 125 mg Capsule is a targeted anticancer therapy containing palbociclib, a cyclin-dependent kinase inhibitor. It is indicated for the treatment of hormone receptor-positive, human epidermal growth factor 2 negative advanced or metastatic breast cancer. The medication is administered in combination with other anticancer agents.

Common adverse effects associated with Palbo 125 mg Capsule include nausea, vomiting, diarrhoea, fatigue, alopecia, dry skin, rash, infections, epistaxis, decreased appetite, low blood cell counts, oedema of lips and mouth, dysgeusia, dry eye, blurred vision, and increased lacrimation. Inform your doctor if these effects persist or cause concern.

Advise your healthcare provider of any known hypersensitivity to palbociclib or excipients in this formulation. Prior to commencing treatment, disclose to your doctor any present infections (fever, chills, sore throat), hepatic disorders, renal disorders, or sugar intolerance. Seek immediate medical attention if you develop dry cough, chest pain, or dyspnoea, as these may indicate pulmonary inflammation. Provide a complete list of all concurrent medications, including supplements and herbal preparations, before initiating therapy.

Effective contraception must be maintained during treatment and for at least three weeks following the final dose. This medication is not recommended for patients under 18 years of age.

Uses

Palbo capsule uses are: Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer .

How it works

Palbo 125 mg Capsule works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.

How to Use

Take Palbo 125 mg Capsule exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this capsule as a whole with a glass of water. Avoid crushing, breaking, or chewing the capsule.

Side Effects

palbo side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious: Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising) Lung inflammation (chest pain, dry cough, or difficulty breathing) Common: Tiredness Hair loss Dry skin, rash Infections Low blood cell counts Decreased of appetite Nausea, vomiting Diarrhea Swelling of lips and mouth Changes in taste Nose bleed Dry eye, blurred vision, increased tearing

References

  1. Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
  2. Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
  3. Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029

Safety Advice

Pregnancy: unsafe It is not recommended to take Palbo 125 mg Capsule during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.

Lungs: Consult your doctor It is not unknown whether palbace 100 mg can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe It is not recommended to take Palbo 125 mg Capsule while breastfeeding as it is not known whether it passes into the breast milk.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS