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Palbodel 75mg Tablet

Salt Composition: PALBOCICLIB

₹1641.00₹4671.56

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Palbociclib 125 mg capsule is a targeted anticancer therapy belonging to the class of cyclin-dependent kinase inhibitors. It is indicated in the treatment of hormone receptor-positive, human epidermal growth factor 2 negative advanced or metastatic breast cancer (spread to other parts of the body). The medication is administered in combination with certain other anticancer agents. Cancer occurs when cells multiply in an uncontrolled and abnormal manner.

Common side effects associated with palbociclib 125 mg capsule include nausea, vomiting, diarrhoea, fatigue, hair loss, dry skin, rash, infections, epistaxis, decreased appetite, low blood cell counts, swelling of lips and mouth, taste alterations, dry eye, blurred vision, and increased lacrimation. Inform your doctor if any of these side effects cause concern or persist.

Notify your healthcare provider of any allergy to palbociclib 125 mg capsule and its constituents. Prior to commencing treatment, inform your doctor of any present infections (fever, chills, or sore throat), liver disorders, kidney disorders, or sugar intolerance. Seek immediate medical attention if you develop symptoms such as dry cough, chest pain, or difficulty breathing, as these may indicate lung inflammation. Disclose all medicines, supplements, and herbal preparations you are currently taking before beginning this treatment.

Effective contraception is essential during treatment and for at least three weeks following the final dose. This medication is not recommended for patients under 18 years of age.

Uses

Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.

How it works

Palbopro 125 mg Capsule works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.

How to Use

Take the Palbopro 125 mg Capsule exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this capsule as a whole with a glass of water. Avoid crushing, breaking, or chewing the capsule.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious: Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising) Lung inflammation (chest pain, dry cough, or difficulty breathing) Common: Tiredness Hair loss Dry skin, rash Infections Low blood cell counts. Decreased of appetite Nausea, vomiting

Expert Tips

During Palbopro 125 mg Capsule treatment, it is advised to avoid grapefruit and its juices and preparations containing St. John's wort. It is recommended to use effective birth control while receiving treatment as well as for at least three weeks after the final dose for females and at least fourteen weeks after the final dose for males. This medication may reduce fertility, so discuss with the physician if you have any concerns. Your doctor may recommend regular blood tests to determine whether Palbopro 125 mg Capsule affects your blood cells.

References

  1. Pfizer Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 26 Nov 2022], https://www.medicines.org.uk/emc/files/pil.4449.pdf
  2. Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
  3. Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
  4. Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029

Safety Advice

Pregnancy: unsafe It is not recommended to take Palbopro 125 mg Capsule during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.

Lungs: Consult your doctor You need to tell your physician if you have any lung disorders before taking Palbopro 125 mg Capsule, as this medication should be used with caution in kidney disorder patients.

Breastfeeding: unsafe It is not recommended to take Palbopro 125 mg Capsule while breastfeeding as it is not known whether it passes into the breast milk. consult your healthcare provider before taking this capsule.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS