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Palborest 75mg Tablet

Salt Composition: PALBOCICLIB

₹1155.00₹1443.75

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Palborest 75mg Tablet contains the active ingredient Palbociclib, a cyclin-dependent kinase inhibitor used in anticancer therapy. It is indicated for treating hormone receptor-positive, human epidermal growth factor 2 negative advanced or metastatic breast cancer. The medication is administered in combination with certain other anticancer agents.

Patients with this condition should be aware of potential side effects associated with Palborest 75mg Tablet. These include nausea, vomiting, diarrhoea, tiredness, hair loss, dry skin, rash, infections, nose bleed, decreased appetite, low blood cell counts, swelling of lips and mouth, changes in taste, dry eye, blurred vision, and increased tearing. Inform your doctor if any of these effects occur or persist.

Prior to commencing treatment, inform your healthcare provider of any allergies to Palborest 75mg Tablet or its ingredients. It is essential to disclose existing conditions including signs of infections (fever, chills, or sore throat), liver disorders, kidney disorders, or intolerance to certain sugars. Report immediately to your physician if you experience dry cough, chest pain, or difficulty breathing, as these may indicate lung inflammation.

Provide a complete list of all medications, supplements, and herbal medicines to your doctor before starting this treatment. Effective birth control should be used during treatment and for at least three weeks following the final dose. This medication is not recommended for patients under 18 years of age.

Uses

Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.

How it works

Palborest 75mg Tablet works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.

How to Use

Take Palborest 75mg Tablet exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this capsule as a whole with a glass of water. Avoid crushing, breaking, or chewing the capsule.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious: Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising) Lung inflammation (chest pain, dry cough, or difficulty breathing) Common: Tiredness Hair loss Dry skin, rash Infections Low blood cell counts Decreased of appetite Nausea, vomiting Diarrhea Swelling of lips and mouth Changes in taste Nose bleed Dry eye, blurred vision, increased tearing

Expert Tips

During Palborest 75mg Tablet treatment, it is advised to avoid grapefruit and its juices and preparations containing St. John's wort. It is recommended to use effective birth control while receiving treatment as well as for at least three weeks after the final dose for females and at least fourteen weeks after the final dose for males. This medication may reduce fertility, so discuss with the physician if you have any concerns. Your doctor may recommend regular blood tests to determine whether Palborest 75mg Tablet affects your blood cells.

References

  1. Pfizer Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 26 Nov 2022], https://www.medicines.org.uk/emc/files/pil.4449.pdf
  2. Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
  3. Neha S Mangini et al; Palborest 75mg Tablet: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
  4. Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029

Safety Advice

Pregnancy: unsafe It is not recommended to take Palborest 75mg Tablet during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.

Lungs: Consult your doctor Inform your physician if you have any lung disorders before taking Palborest 75mg Tablet, as it should be used with caution in liver disorder patients.

Breastfeeding: unsafe It is not recommended to take Palborest 75mg Tablet while breastfeeding as it is not known whether it passes into the breast milk.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS