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Paleno 125mg Capsule
Salt Composition: PALBOCICLIB
- Manufacturer: SUN PHARMACEUTICAL INDUSTRIES LTD
- Pack Size: 21 CAPSULE(s) IN A BOTTLE
- Dosage Form: CAPSULE
- Strength: 125MG
- Prescription Required
₹4650.00₹5811.56
Inclusive of all taxes
Product Introduction
Paleno 125 mg Capsule is a targeted therapy containing the active constituent palbociclib. This palbociclib capsule belongs to the group of anticancer medications known as cyclin-dependent kinase inhibitors. Paleno is indicated for hormone receptor-positive, human epidermal growth factor 2 negative advanced or metastatic breast cancer. Cancer is a condition in which cells multiply in an uncontrolled and abnormal manner. It is given in combination with certain other anticancer medications. The side effects likely to be associated with Paleno 125 mg Capsule are nausea, vomiting, diarrhoea, tiredness, hair loss, dry skin, rash, infections, nose bleed, decreased appetite, low blood cell counts, swelling of lips, mouth, changes in taste, dry eye, blurred vision, and increased tearing. Inform your doctor if any of these side effects disturb or persist. Inform your healthcare provider if you are allergic to Paleno 125 mg Capsule and its ingredients. Before taking this medicine, it is vital to inform your doctor if you have any signs of infections (fever, chills, or sore throat), liver disorders, kidney disorders, or intolerance to some sugars. The dosage typically consists of taking one 125 mg capsule once daily for 21 consecutive days followed by a 7-day break, completing a 28-day cycle. Dosage may be adjusted depending on your body's response and blood test results, so follow your doctor's instructions closely.
Uses
The paleno 125mg uses are: Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.
How it works
Paleno 125 mg Capsule works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.
How to Use
Take Paleno 125 mg Capsule exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this capsule as a whole with a glass of water. Avoid crushing, breaking, or chewing the capsule.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. paleno capsule side effects include Serious side effects of Paleno 125mg Capsules are: Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising) Lung inflammation (chest pain, dry cough, or difficulty breathing) Common side effects of Paleno 125mg Capsules are: Tiredness Hair loss Dry skin, rash Infections Low blood cell counts Decreased of appetite Nausea, vomiting Diarrhea Swelling of lips and mouth Changes in taste Nose bleed Dry eye, blurred vision, increased tearing
Expert Tips
Avoid grapefruit and St. John's wort: Do not consume grapefruit, grapefruit juice, or any products containing St. John’s wort during treatment with Paleno 125 mg Capsule. Use birth control: Females: Use effective contraception during treatment and for at least 3 weeks after the final dose. Males: Use contraception for at least 14 weeks after the final dose. Possible fertility effects: This medicine may reduce fertility; speak with your doctor if you have concerns about future family planning. Regular blood tests: Your doctor may recommend routine blood tests to monitor how the medication affects your blood cells. Substitute options: If needed, your doctor might prescribe a suitable alternative to Paleno 125 mg Capsule 21's based on your health and treatment needs.
References
- Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
- Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
- Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029
Safety Advice
Pregnancy: unsafe It is not recommended to take Paleno 125 mg Capsule during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.
Lungs: Consult your doctor It is not unknown whether Paleno 125mg Capsule can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe It is not recommended to take Paleno 125 mg Capsule while breastfeeding as it is not known whether it passes into the breast milk.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.