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Parihep 40mg Injection

Salt Composition: ENOXAPARIN

₹299.00₹470.33

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Parihep 40mg Injection

Categories: Others

Conditions: Anticoagulants

Product Introduction

Parihep 40mg Injection is an anticoagulant belonging to the low molecular weight heparin (LMWH) class. The active ingredient is Enoxaparin. It is indicated for treatment of severe blood clots and prevention of deep vein thrombosis following abdominal surgery, hip replacement surgery, knee replacement surgery, and in patients with severe immobility. This injection is also used to prevent further cardiac complications in patients with unstable angina and non-Q wave myocardial infarction.

Parihep 40mg Injection is contraindicated in patients with active bleeding, hypersensitivity or allergies to the active ingredient, and those with a history of heparin-induced thrombocytopenia. Prior to administration, inform your physician if you have allergy to Enoxaparin, heparin, benzyl alcohol, or pork products. Your healthcare provider will monitor you regularly for signs of bleeding. Notify your physician if you have kidney problems. Use is not recommended in children and adolescents below 18 years of age. Parihep 40mg Injection should not be used if you are undergoing neuraxial anaesthesia or spinal puncture procedures. Older adults and patients with low body weight require monitoring for increased bleeding risk. Inform your physician if you are pregnant, breastfeeding, or planning pregnancy. In pregnant women with artificial heart valves, Parihep 40mg Injection may increase bleeding risk and close monitoring is necessary.

Before commencing Parihep 40mg Injection, avoid hemostatic drugs unless absolutely necessary. Inform your physician of all medications you are taking, including herbal and vitamin supplements.

Uses

Parihep 40mg Injection is used in the treatment of the following: Treatment of deep vein thrombosis Prophylaxis of venous thrombo-embolism Treatment of unstable angina Treatment of ST-segment Elevation Myocardial Infarction (STEMI) Prevention of blood clots during surgeries

How it works

Parihep 40mg Injection binds to the antithrombin to form a complex. Antithrombin is a protein that blocks the formation of abnormal blood clots. This drug mainly prevents the activation of factor Xa, eventually preventing clot formation. It is commonly used for the prevention and treatment of conditions associated with increased risk of blood clots.

How to Use

Parihep 40mg Injection will be administered to you by a healthcare professional in a hospital setting. It is usually administered as an intravenous injection into a vein. Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious side effects of Parihep 40mg Injection are: Severe allergic reactions (swelling of lips, tongue, or throat, difficulty breathing, or swallowing) Too much bleeding (weakness, being pale, dizziness with headache, or unexplained swelling) Blockage of blood vessels (pain, redness, or swelling in the legs, or coughing up blood) Rash of dark red spots under the skin Common side effects of Parihep 40mg Injection are: Bleeding Bruising more easily Low blood cell counts Headache Itchy red skin Edema Pain at the injection site Pink patches on the skin

Expert Tips

Parihep 40mg Injection can cause bleeding and many undesirable side effects; hence it is advised to get adequate rest during the treatment. Eat a well-balanced diet. Apply a cool compress at the injection site to reduce pain and irritation. Parihep 40mg Injection should not be stopped suddenly without first talking to your doctor because doing so may raise your risk of blood clots. Aspirin and other nonsteroidal anti-inflammatory medicines (NSAIDs) may increase the risk of bleeding when combined with Parihep 40mg Injection, so it is not recommended to take them without first talking to your doctor. Keep away from activities that put you at higher risk of bleeding or getting hurt, like contact sports and activities. Foods high in vitamin K may have an impact on blood clotting and may interfere with the way anticoagulant drugs like Parihep 40mg Injection. It is recommended to eat leafy green vegetables, asparagus, Brussels sprouts and soybean oil in moderation. It is advised to monitor your platelet count regularly.

References

  1. 1. Rovi Pharma Industrial ServicesElectronic Medicines Compendium (EMC), [Revised on Apr 2022], [Accessed on March 2024], https://www.medicines.org.uk/emc/files/pil.9331.pdf 2. Sanofi, [Revised on Apr 2022] [Accessed on March 2024], https://products.sanofi.us/lovenox/lovenox.pdf 3. Sanofi India Limited, Central Drugs Standard Control Organisation (CDSCO), [Revised on Dec 2018], [Accessed on March 2024], https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadPrescribingInfo/1CLEXANE-SANOFI.pdf 4. KD Tripathi, Essentials of Medical Pharmacology, Drugs Affecting Coagulation, Bleeding and Thrombosis, 8th Edition, 2019, 659-681. 5. https://www.ema.europa.eu/en/documents/product-information/inhixa-epar-product-information_en.pdf

Safety Advice

Pregnancy: Consult your doctor Before beginning therapy with Parihep 40mg Injection, tell your doctor if you are pregnant, suspect you are pregnant, or are planning to become pregnant. It is not known that Parihep 40mg Injection interferes with pregnancy.

Lungs: Consult your doctor It is unknown whether Parihep 40mg Injection is safe for patients with lung problems. Consult your doctor if you have lung disease before starting the treatment.

Breastfeeding: Consult your doctor It is unknown if Parihep 40mg Injection is excreted unaltered in breast milk. Please consult your doctor before breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS