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Pazib 400mg Tablet
Salt Composition: PAZOPANIB
- Manufacturer: GLENMARK PHARMACEUTICALS LTD
- Pack Size: 30 TABLET(s) IN A BOTTLE
- Dosage Form: TABLET
- Strength: 400MG
- Prescription Required
- Storage: Store Pazib 400mg tablet in room temperature (25°C) Keep the injection away from the reach of children and pets. If you forgot to take a dose, take it as soon as you remember. However, skip the missed dose if it is nearly time for the next dose. Do not take a double dose to make up for a forgotten dose.
₹3121.00₹3900.94
Inclusive of all taxes
Product Introduction
Pazib 400mg tablet contains the active substance pazopanib. It is an antineoplastic drug belonging to the class of tyrosine kinase inhibitors. It is used in adults to treat advanced kidney cancer or cancer that has spread to other organs. It is also indicated for the treatment of certain forms of soft-tissue sarcoma, a type of cancer affecting the supportive tissues of the body. This medicine works by preventing the activity of proteins involved in the growth and spread of cancer cells. Do not take Pazib 400mg tablet if you are allergic to pazopanib or any other ingredients of this medicine. Before starting treatment, inform your doctor if you have kidney, heart, lung, or liver problems, bleeding disorders, stomach or bowel problems, and thyroid problems. This tablet can raise your blood pressure. It is necessary to check your blood pressure regularly during treatment. No dose adjustments are required for patients with kidney diseases. Your doctor will advise you to stop Pazib 400mg tablet at least 7 days before any surgery or dental operations you are undergoing, as it may affect wound healing. This medicine is not recommended for people aged under 18 years. This medicine can cause infertility; consult your doctor before taking this medicine. The most common side effects are diarrhoea, hypertension, hair colour changes, nausea, and vomiting.
Uses
Advanced renal cell carcinoma Advanced soft tissue sarcoma
How it works
Pazib 400mg tablet is a biological agent that acts as targeted drug therapy in cancer treatment. It is an anticancer medication that belongs to the category of tyrosine kinase inhibitors. It interferes with the growth of blood vessels inside the cancer cells by acting against a protein called Vascular Endothelial Growth Factors (VEGF) to shrink cancer cells, ultimately stopping their growth and multiplication.
How to Use
Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Take the tablets as prescribed by your doctor. Do not break, crush, or chew the tablets. Swallow the tablet whole with a glass of water. Do not take this medicine with food, as it affects the absorption of this medicine. Take Pazib 400mg tablet at least two hours after a meal or one hour before a meal.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Hypertension Hair color change Increased glucose levels Decreased weight, decrease in appetite Diarrhea Nausea, vomiting Muscle and joint pain Headache Shortness of breath Tiredness Serious Heart problems Bleeding from the anus, mouth Hypothyroidism Interstitial lung disease Infections
Expert Tips
Do not drink grapefruit juice during the treatment with this medicine, as this may increase the chance of side effects. Male patients with female partners with reproductive potential should use effective contraception during the treatment and at least 2 weeks after the last dose to prevent pregnancy. Take the tablet at about the same time each day. Your doctor will regularly do lab tests to check whether the medicine works for you.
References
- Highlights Of Prescribing Information - Pazopanib. [Revised on 2021] [cited 2023 Mar 24]. Available from: https://www.novartis.com/us-en/sites/novartis_us/files/votrient.pdf
- Summary Of Product Characteristics - Pazopanib. [revised on 2021] [cited 2023 Mar 24]. Available from: https://www.ema.europa.eu/en/documents/product-information/votrient-epar-product-information_en.pdf
- Votrient 400 mg film coated tablets - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. 2021 [cited 2023 Mar 24]. Available from: https://www.medicines.org.uk/emc/product/572/smpc
- Edward Chu, Cancer Chemotherapy, Langeâs Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
Safety Advice
Pregnancy: unsafe Pazib 400mg tablet is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for at least 2 weeks after your last dose is necessary.
Lungs: Consult your doctor It is unknown whether Pazib 400mg tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Pazib 400mg tablet because the medicine passes into the breast milk in small amounts and may harm your baby.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.