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PEG-LASGEN 3750IU Injection

Salt Composition: PEG L-ASPARAGINASE

₹25915.00₹32393.71

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

PEG-LASGEN 3750IU Injection contains peg-L-asparaginase. It is used to treat Acute Lymphoblastic Leukaemia (cancer of white blood cells) in patients aged four months and above. In Acute Lymphoblastic Leukaemia, the white blood cells called lymphocytes multiply uncontrollably and abnormally. This disorder is also known as Acute Lymphocytic Leukaemia. This medicine should not be used if you have severe problems with your pancreas or are allergic to asparaginase or any of the ingredients of this medicine. Speak to your physician if you are a diabetic patient, as this medicine contains glucose. The common side effects of PEG-LASGEN 3750IU Injection are muscle pain, nausea, infections, abdominal pain, and diarrhoea. Use effective birth control during treatment with PEG-LASGEN 3750IU Injection and for at least three months after the last dose. Women should use contraception methods other than oral contraceptives.

Uses

Acute Lymphoblastic Leukemia (ALL)

How it works

Cancer cells need a substance called asparagine to survive. PEG-LASGEN 3750IU Injection works by lowering the levels of asparagine in the body.

How to Use

Your healthcare professional will give it to you. Your doctor will decide the dose and dosage of your treatment based on the disease condition and other factors. Do not self-administer.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious: Severe allergic reactions High blood sugar levels Bleeding Liver and nervous problems Pain near your stomach (inflammation of the pancreas) Blood clots in arm or leg Pain, bruising, swelling, or hardening of the skin at the injection site Common: Nausea Muscle pain Weight loss Infections (fever, rapid heart rate, confusion, or a rash) Difficulty breathing Inflammation of the digestive tract Diarrhea Abdominal pain, discomfort Headache Tiredness

Expert Tips

This injection should be administered only by the doctor or nurse. Inform the doctor if the patient has any allergic response, blood pressure, kidney, liver problems and medication taken for different medical conditions. Consult the doctor if the patient is pregnant or breastfeeding mother before taking this medication. Avoid driving while taking this medication as it can cause dizziness. Avoid handling heavy machineries as the patient may lack concentration.

References

  1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1720.
  2. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 869.
  3. Porton Biopharma Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 9th August 2021], https://www.medicines.org.uk/emc/files/pil.12340.pdf
  4. Merck & Co., Inc., US Food and Drug Administration, [Issued on 2000] [ Accessed on 5th August 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2002/aspamer080102LB.pdf

Safety Advice

Pregnancy: unsafe You should not take Peg-L-asparaginase if you are pregnant or planning to get pregnant because it may cause birth defects.

Lungs: Consult your doctor Limited information is available on the safety of Peg-L-Asparaginase in patients with lung problems. Inform your physician if you have lung disease or disorders before initiating the treatment.

Breastfeeding: unsafe You must not breastfeed your baby during treatment with PEG-LASGEN 3750IU Injection. You need to tell your physician if you are breastfeeding before taking this medicine.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS