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Pegadria 20mg Injection
Salt Composition: PEGYLATED LIPOSOMAL DOXORUBICIN
- Manufacturer: INTAS PHARMACEUTICALS LTD
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 20MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Keep Pegadria 20mg Injection out of sight and reach of children. Store refrigerated at 2°C - 8°C. Do not freeze.
₹2557.00₹3169.00
Inclusive of all taxes
Product Introduction
Pegadria 20mg Injection is an anticancer medication containing doxorubicin encapsulated within a closed lipid sphere (liposome). Cancer is characterised by uncontrolled and abnormal cell multiplication. This medication is indicated for breast cancer, ovarian cancer, multiple myeloma (cancer of plasma cells, a type of white blood cell), and AIDS-related Kaposi's sarcoma. Patients with HIV infection face the highest risk of developing Kaposi's sarcoma, a cancer that forms in the lining of lymph and blood vessels. Pegadria 20mg Injection may be administered as monotherapy or in combination with other anticancer medicines. This medication is not recommended for adolescents and children. Effective birth control should be used during treatment and for at least six months after the final dose. It is important to inform your doctor if you have allergies to peanuts or soya, are receiving medicines for heart or liver disorders, have diabetes, Kaposi's sarcoma, or have oral problems before initiating Pegadria 20mg Injection.
Uses
Breast cancer Ovarian cancer Multiple myeloma AIDS-related Kaposiâs sarcoma
How it works
Pegadria 20mg injection is a new class of drug formulations delivered in vesicles called liposomes. The mechanism of action of doxorubicin HCl is related to its ability to bind DNA and inhibit nucleic acid synthesis. Studies have demonstrated that the drug penetrates rapidly into the cell, binds to certain proteins in DNA, and thereby inhibits cell division and nucleic acid synthesis.
How to Use
Your dose and frequency of administration will be decided by your physician based on your disease condition and other factors. It will be given to you by a healthcare professional. Do not self-administer.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Fever, tiredness, bruising or bleeding Severe diarrhea, sores in mouth, nausea, vomiting Lung infections, shortness of breath Severe stomach pain Severe weakness Common Low blood cell counts Hair loss Decreased appetite Skin rashes Pain in the muscles and joints Constipation Feeling confused, difficulty sleeping Headache, dizziness, sleepiness Change in taste High or low blood pressure Excessive sweating Pain when passing urine Weight loss Muscle spasms Fast heartbeat
Expert Tips
Avoid prolonged sun exposure and unnecessary heat exposure (such as hot dishwater and long hot baths). Avoid pressure on elbows, knees, and soles of feet (such as leaning on elbows, kneeling, and long walks). Wear loose clothing. Keep this medicine out of sight and reach of children. Store the tablets at room temperature. Avoid keeping the tablet in direct sunlight or excessive moisture. Pegylated liposomal doxorubicin may cause dizziness. If you are affected by this side effect, do not drive, use machinery, or do anything that needs alert until you can do it safely.
References
- Goodman & Gilmanâs, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1714.
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 867.
- Baxter Holding BV, European medicines agency (ema), [Revised on May 2006] [ Accessed on 4th Dec 2021], https://www.ema.europa.eu/en/documents/product-information/caelyx-pegylated-liposomal-epar-product-information_en.pdf
- Ben Venue Laboratories, Inc, US Food and Drug Administration, [Revised on May 2007] [ Accessed on 4th Dec 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/050718s029lbl.pdf
Safety Advice
Pregnancy: unsafe Pegadria 20mg Injection may harm the unborn baby. You need to tell your physician if you are pregnant or planning to get pregnant before taking this medicine.
Lungs: Consult your doctor It is unknown whether Pegadria 20mg Injection can be given to patients with lung diseases. Please consult your physician if you have any lung problems.
Breastfeeding: unsafe Stop breastfeeding before starting treatment with Pegadria 20mg Injection. You need to tell your physician if you are breastfeeding before taking this medicine.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.