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Pegihep 100mcg Injection
Salt Composition: PEGYLATED INTERFERON ALPHA-2B
- Manufacturer: ZYDUS CADILA
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 100MCG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Store Pegihep 100mcg Injection at controlled room temperature at (25°C). Do not freeze. Keep it out of reach from children.
₹6023.00₹7084.59
Inclusive of all taxes
Product Introduction
Pegihep 100mcg Injection is an antineoplastic medicine in the interferon class, containing Pegylated Interferon Alpha-2B. It is indicated for chronic hepatitis C infection in patients aged 18 years and above with compensated liver disease. Hepatitis C is a viral infection affecting the liver, transmitted through contact with infected blood, sharing of needles or injection equipment, and less commonly through sexual contact, sharing of personal hygiene items, or from mother to infant during childbirth.
Use this medicine with caution in patients with creatinine clearance below 50 mL/min, indicating moderate to severe renal impairment. Reduced renal clearance may increase medication accumulation and risk of toxicity and adverse effects. Dosage reduction is necessary in these patients, who require close monitoring for signs of toxicity including fatigue, depression, or decreased white blood cell count. Dose adjustment is mandatory in patients with renal impairment.
Inform your healthcare provider before starting treatment if you are pregnant or planning pregnancy. This drug may cause harm to an unborn baby. Both men and women should use appropriate contraceptive methods during treatment and for one week after the final dose of Pegihep 100mcg Injection. Avoid breastfeeding during treatment, as this drug passes into breast milk and may affect infant growth and development.
Do not take this injection if you are allergic to the active ingredient or any component of the formulation. Report any signs of allergic reaction immediately to your doctor, including hives, difficulty breathing, or swelling of the face or throat. This drug is contraindicated in patients with decompensated liver disease, a serious condition where severe liver damage impairs normal function. Use of this medicine is not advised in such patients.
Uses
The Pegihep 100mcg Injection is used in the treatment of the following: Chronic Hepatitis C (CHC) Adjuvant therapy to surgery for malignant melanoma
How it works
Pegihep 100mcg Injection works by stimulating the body's immune system to fight off viral infections and cancer cells. Specifically, it activates certain immune cells, such as natural killer cells and T-cells, to attack and eliminate the infected virus or cancerous cells.
How to Use
Pegihep 100mcg Injection is administered as a subcutaneous injection (under your skin). If this drug is recommended for you, it will be given by a doctor. Do not self-administer. The recommended dose is 1.5 micrograms/kg/week. Your doctor will choose the dosage and administration frequency based on the condition because it differs from person to person.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious side effects of Pegihep 100mcg Injection are: Low or high BP Increased heart rate Depression Common side effects of Pegihep 100mcg Injection are: Tiredness Flu-like symptoms Headache Loss of appetite Hair loss Muscle pain Anxiety Anaemia Irritability Insomnia Fainting Eye irritation and disturbance Injection site reactions Weight loss
Expert Tips
Pegihep 100mcg Injection can make you feel dizzy and weak. Avoid driving or operating heavy machines if you experience dizziness, confusion, or tiredness while on treatment with this drug. This drug may affect liver function and blood cell counts, and regular monitoring is necessary to ensure that the medication is not causing any harm. This medicine can reduce the body's immune response, which may increase the risk of infection. Therefore, it is important to avoid contact with people who are sick and it is advised to practice good hand hygiene. It is advised to keep the injection out of reach of children and pets. If medication is no longer needed or has expired, it should be disposed of properly and not kept in the household trash.
References
- Biocon, [Revised on Aug 2015] [Accessed on 26th Jul 2021], https://www.biocon.com/docs/prescribing_information/virology/CimiPeg_PI_v1.pdf
- Schering Corporation, US Food & Drug Administration, [Revised on 26th Sep 2003] [Accessed on 26th Jul 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2001/pegsche080701lb.htm
- Q.M. Anstee, D.E.J. Jones, Liver and biliary tract disease, Davidson's Principles and Practice of Medicine, 22nd Edition, 2014, 921-988.
- KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
Safety Advice
Pregnancy: unsafe Pegihep 100mcg Injection is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Lungs: Consult your doctor It is not known whether Pegihep 100mcg Injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe It is unsafe to breastfeed during treatment with Pegihep 100mcg Injection because it may cause harm to the baby. Please consult your doctor before breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.