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Pegihep 80mcg Injection
Salt Composition: PEGYLATED INTERFERON ALPHA-2B
- Manufacturer: ZYDUS CADILA
- Pack Size: 1 VIAL(s) OF 0.5ML
- Dosage Form: INJECTION
- Strength: 80MCG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Store Pegihep 80mcg injection in the controlled room temperature at (25°C). Do not freeze. Keep it out of reach from children.
₹5668.00₹7084.59
Inclusive of all taxes
Product Introduction
Pegihep 80mcg injection is an antineoplastic drug belonging to the class of interferons, containing the active ingredient Pegylated Interferon Alpha-2B. It is indicated for the treatment of chronic hepatitis C infection in patients above 18 years of age with compensated liver disease. Hepatitis C infection is a viral infection affecting the liver. This infection can spread through contact with infected blood, by sharing needles or other drug injection equipment, or less commonly through sexual contact, sharing personal hygiene items, or from mother to baby during childbirth.
This medicine should be used with caution in patients with creatinine clearance below 50 mL/min, as this indicates moderate to severe impairment of renal function. This can lead to slower clearance of the medication, which may increase the risk of toxicity and adverse effects. The dosage should be reduced in these patients, and they should be closely monitored for signs of toxicity, such as fatigue, depression, or decreased white blood cell count. Dose adjustment is therefore necessary in patients with renal impairment.
Inform your healthcare provider before beginning this treatment if you are pregnant or planning to have a baby. As this drug may cause harm to an unborn baby, both men and women are advised to follow proper contraceptive methods during and one week after the last dose of Pegihep 80mcg injection. Avoid breastfeeding while on treatment, as this drug can impact the growth and development of the baby by passing into the breast milk.
This injection is not recommended if you are allergic to the drug or any of its ingredients. If you experience any signs of an allergic reaction, such as hives, difficulty breathing, or swelling of the face or throat, report to your doctor immediately.
This drug is contraindicated in patients with decompensated liver disease, a serious condition where the liver is severely damaged and is no longer able to function properly. Taking this medicine in such cases is highly inadvisable.
Uses
Chronic Hepatitis C (CHC)
How it works
Pegihep 80mcg injection works by stimulating the body's immune system to fight off viral infections and cancer cells. Specifically, it activates certain immune cells, such as natural killer cells and T-cells, to attack and eliminate the infected virus or cancerous cells.
How to Use
Pegihep 80mcg injection injection is administered as a subcutaneous injection (under your skin). If this drug is recommended for you, it will be given by a doctor. Do not self-administer. the recommended dose is 1.5 micrograms/kg/week. Your doctor will choose the dosage and administration frequency based on the condition because it differs from person to person.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Low or high BP Increased heart rate Depression Common Tiredness Flu-like symptoms Headache Loss of appetite Hair loss Muscle pain Anxiety Anaemia Irritability Insomnia Fainting Eye irritation and disturbance Injection site reactions Weight loss
Expert Tips
Pegihep 80mcg injection can make you feel dizzy and weak. Avoid driving or operating heavy machines if you experience dizziness, confusion, or tiredness while on treatment with this drug. This drug may affect liver function and blood cell counts, and regular monitoring is necessary to ensure that the medication is not causing any harm. This medicine can reduce the body's immune response, which may increase the risk of infection. Therefore, it is important to avoid contact with people who are sick and it is advised to practice good hand hygiene. It is advised to keep the injection out of reach of children and pets. If medication is no longer needed or has expired, it should be disposed of properly and not kept in the household trash.
References
- Biocon, [Revised on Aug 2015] [Accessed on 26th Jul 2021], https://www.biocon.com/docs/prescribing_information/virology/CimiPeg_PI_v1.pdf
- Schering Corporation, US Food & Drug Administration, [Revised on 26th Sep 2003] [Accessed on 26th Jul 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2001/pegsche080701lb.htm
- Q.M. Anstee, D.E.J. Jones, Liver and biliary tract disease, Davidson's Principles and Practice of Medicine, 22nd Edition, 2014, 921-988.
- KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
Safety Advice
Pregnancy: unsafe Pegihep 80mcg injection is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Lungs: Consult your doctor It is not known whether Pegihep 80mcg injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe It is unsafe to breastfeed during the treatment with Pegihep 80mcg injection because it may cause harm to the baby. Please consult your doctor before breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.