PemeSYM 500 Injection

PemeSYM 500 Injection contains Pemetrexed, an anticancer medicine classified as an antifolate agent. It is primarily used to treat non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma, a cancer affecting the lining of the lungs. Depending on the condition, it may be administered alone or in combination with other chemotherapy medicines such as cisplatin. To help reduce the risk of side effects, your doctor may also prescribe folic acid, vitamin B12, and corticosteroids before and during treatment.

Before each dose, regular blood tests are performed to monitor your kidney and liver function and ensure your blood cell counts are suitable for treatment. Inform your doctor if you have a history of kidney disease, heart problems, fluid around the lungs, recent radiotherapy, or vaccinations. Women should avoid becoming pregnant during treatment and for at least 6 months after the final dose, while men are advised not to father a child during treatment and for 3 months afterward due to potential fertility risks. PemeSYM 500 Injection is not recommended for children or adolescents below 18 years of age.

Malignant pleural mesothelioma Non-small cell lung carcinoma

PemeSYM 500 Injection inhibits the mechanism required for cell division and replication by blocking specific enzymes involved in folate metabolism (essential for cell replication) and DNA synthesis, which will prevent the cancer cells from growing and multiplying.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Blood infection Severe allergic reaction Breathlessness, intense chest pain or cough with bloody sputum Reduced neutrophil granulocytes (white blood cells) Kidney failure Pharyngitis (a sore throat) Abnormal liver function Common Fatigue Nausea, vomiting, diarrhea Redness, swelling or sores in the mouth Loss of appetite, sensation Reduced hemoglobin level Increased skin pigmentation Watery and inflamed eyes, taste change Fever Muscle weakness Dehydration Constipation Skin rash Hair loss

Do not plan for pregnancy during treatment. Men should avoid fathering a child during treatment and for at least 3 months after the final dose. Discuss any fertility concerns with your doctor before starting this medication. Inform your doctor immediately if you experience any symptoms listed under side effects. Let your doctor know if you have undergone radiotherapy, taken any vaccines, or are using other medications, as they may reduce the effectiveness of this medicine or increase side effects. Share your medical history with your doctor, especially if you have or had heart disease, kidney issues, or liver problems.