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Pemetrex 100mg Injection
Salt Composition: PEMETREXED
- Manufacturer: BDR PHARMACEUTICALS INTERNATIONALS PVT LTD
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 100MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Keep the tablets away from light and moisture. Store refrigerated at 2°C to 8°C. Keep the tablets out of the reach of children and animals.
₹686.00₹857.30
Inclusive of all taxes
Product Introduction
Pemetrex 100 mg/vial (injection) is an anticancer medicine containing the active ingredient pemetrexed. It belongs to the antifolate agent class of medications. Pemetrex injection is used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma (cancers of the lungs and chest). This injection is given alone or in combination with another anticancer medicine, such as cisplatin. Your doctor may prescribe corticosteroids, folic acid, and vitamin B12 to manage the side effects. Blood tests will be taken before each infusion to assess whether your kidney and liver functions are adequate and whether you have sufficient blood cells to receive this medicine.
Before starting treatment with Pemetrex 100 mg injection, it is important to inform your physician if you currently have or have previously had any medical conditions including kidney problems, heart disorders, or fluid accumulation in the lungs. Report to your doctor if you have recently had or are currently undergoing radiotherapy or any vaccination before taking this medication. Inform your doctor immediately if you are planning to get pregnant or think you may be pregnant. Use effective birth control during treatment and for at least six months after the last dose of Pemetrex 100 mg injection. In men, it is recommended not to father a child during and up to three months after treatment. It is advised to discuss fertility concerns with your doctor. This medication is not recommended for adolescents and children under 18 years of age.
Uses
Pemetrex 100mg uses are Malignant pleural mesothelioma Non-small cell lung carcinoma
How it works
Pemetrex 100mg inhibits the mechanism required for cell division and replication by blocking specific enzymes involved in folate metabolism (essential for cell replication) and DNA synthesis, which will prevent the cancer cells from growing and multiplying.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Pemetrex 100mg side effects are Serious: Blood infection Severe allergic reaction Breathlessness, intense chest pain or cough with bloody sputum Reduced neutrophil granulocytes (white blood cells) Kidney failure Pharyngitis (a sore throat) Abnormal liver function Common: Fatigue Nausea, vomiting, diarrhea Redness, swelling or sores in the mouth Loss of appetite, sensation Reduced hemoglobin level Increased skin pigmentation Watery and inflamed eyes, taste change Fever Muscle weakness Dehydration Constipation Skin rash Hair loss
References
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs,7th edition, 2013, 863.
- Eagle Pharmaceuticals, US Food and Drug Administration, [ Revised on Feb 2020] [ Accessed on 27 - March - 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/209472s000lbl.pdf
- Seacross Pharmaceuticals Ltd, Electronic medicines compendium (emc), [ Accessed on 27 - March - 2023], https://www.medicines.org.uk/emc/files/pil.8887.pdf
Safety Advice
Pregnancy: unsafe Do not take Pemetrex 100mg if you are pregnant because it may cause harm to the unborn baby. Consult your doctor before starting the treatment
Lungs: Consult your doctor Consult your doctor if you experience any symptoms like; shortness of breath, blockage, or inflammation in the lining of the lung while taking Pemetrex 100mg injection
Breastfeeding: unsafe It is unsafe to breastfeed while taking Pemetrex 100mg because it can cause toxicity to the baby. If you are breastfeeding a baby, it has to be discontinued. Please consult your physician for more advice.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.