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Pharmoxal 100mg Injection

Salt Composition: OXALIPLATIN

₹999.00₹5915.60

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Pharmoxal 100mg Injection is a platinum-based antineoplastic agent containing oxaliplatin. It is prescribed for stage 3 colon cancer following surgical resection of the primary tumour, and for metastatic colon and rectal cancer. The medicine is used in combination with other anticancer drugs. Colorectal cancer typically develops in the rectum and large intestine from the accumulation of various genetic mutations. Both environmental and genetic factors contribute to colorectal cancer development. Pharmoxal 100mg Injection is effective against tumours that are resistant to cisplatin therapy. Common side effects include reduced blood cell count, unpleasant sensation in the throat, diarrhoea, nausea, vomiting, indigestion, heartburn, blood clots, blood in urine, high blood pressure, depression, insomnia, and low calcium level. Inform your doctor if these side effects are bothersome or persist. Tell your doctor if you are allergic to oxaliplatin or any ingredients in Pharmoxal 100mg Injection. Before beginning treatment, inform your physician if you have moderate or mild kidney problems, liver problems, or heart disorders. Disclose all medications you are taking, including vaccinations, to your doctor. This medicine is not recommended for pregnant or breastfeeding women.

Uses

The uses of Pharmoxal 100mg Injection include: Treatment of colon and rectal cancer.

How it works

Pharmoxal 100mg Injectionworks by damaging the genetic material, such as DNA and RNA of the cancer cells, that interferes with the growth of cancer cells. It stops their growth and multiplication of cancer cells.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious side effects of Pharmoxal 100mg Injection are: Abnormal bleeding or bruising Severe allergic reactions Continuous diarrhea and vomiting Sore throat and fever Irregular heartbeat Muscle pain and weakness Mouth ulcers Extreme tiredness and breathlessness Headache Altered mental function Blurred vision Seizures Common side effects of Pharmoxal 100mg Injection are: A reduced number of blood cells Unpleasant sensation in the throat Diarrhea Nausea, vomiting High risk of infections Indigestion and heartburn Blood in urine Blood clots High BP Depression and insomnia Low levels of calcium in the blood

Expert Tips

Women should use effective birth control for at least 4 weeks before starting and throughout treatment with this medicine. Men are advised to use contraception during treatment and for 6 months after the final dose to avoid fathering a child. Male patients should consult their doctor about sperm preservation before beginning treatment. Pregnant women should not use or handle this medicine, as it contains cytotoxic (cell-damaging) substances. This medicine is handled only by healthcare professionals using sterile, single-use gloves, protective masks, hats, and goggles. Avoid vaccinations during treatment, as they may cause serious side effects when combined with this drug.

References

  1. Hospira UK Limited, Electronic Medicines Compendium (EMC), [Revised on Dec 2020] [Accessed on 25th Jun 2021], https://www.medicines.org.uk/emc/files/pil.6286.pdf
  2. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
  3. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
  4. I.D. Penman, C.W. Lees, Alimentary tract and pancreatic disease, Davidson’s Principles & Practice of Medicine, 22nd Edition, 2014, 837-920.

Safety Advice

Pregnancy: Unsafe Pharmoxal 100mg Injection is unsafe to use during pregnancy; hence, it is not recommended. Women should use effective contraception during and after the 4 months of treatment.

Lungs: Consult Your Doctor Inform your physician before starting treatment with Pharmoxal 100mg Injection if you have lung disease or abnormal liver function. Your physician will prescribe the dose accordingly.

Breastfeeding: Unsafe It is unsafe to breastfeed during treatment with Pharmoxal 100mg Injection. Your physician might suggest you stop breastfeeding for some time, depending on your condition.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS