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Phesgo 600mg/600mg Injection

Salt Composition: PERTUZUMAB,TRASTUZUMAB

₹213750.00₹257207.00

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Phesgo 600mg/600mg Injection is a targeted therapy containing pertuzumab and trastuzumab. It is used to treat human epidermal growth factor receptor 2 positive breast cancer that has spread to other parts of the body (metastatic disease) or breast cancer that has recurred following prior treatment. It may also be administered before or after surgery in patients with non-metastatic disease. Breast cancer develops when cells grow abnormally and uncontrollably. Before receiving Phesgo 600mg/600mg Injection, inform your physician if you have cardiac conditions, have undergone radiotherapy, or have known allergies. This medication is not recommended for children and adolescents under 18 years of age. In patients with early-stage HER2-positive breast cancer, the addition of pertuzumab or trastuzumab to standard chemotherapy can reduce the risk of disease recurrence and improve disease-free survival.

Uses

Phesgo 600mg/600mg Injection is used to manage the following conditions: Breast cancer Non-small cell lung cancer

How it works

Human epidermal growth factor receptor 2 protein is largely present in some cancer cells and stimulates the growth of cancer cells. Phesgo 600mg/600mg Injection binds selectively to the HER2 receptors on breast cancer cells' surface, blocks them from receiving growth signals, and stops the cancer cells' growth.

How to Use

Phesgo 600mg/600mg Injection is a medication administered intravenously (IV) by a healthcare professional. It is important to follow the healthcare provider's instructions regarding the dosage and administration of medication. Do not double the dose to make up for missed doses.

Side Effects

Like all medications, Phesgo 600mg/600mg Injections cause some side effects, although not everyone will experience them. Serious: Pulmonary toxicity (interstitial lung disease or pneumonitis) Infusion-related reactions Hypersensitivity reactions Liver toxicity Immune system effects Severe allergic reactions Gastrointestinal perforation (rare) Reduced blood platelets or white blood cell counts Common: Nausea and vomiting Diarrhea Fatigue Hair loss Rash or itching Muscle pain or weakness Headache Difficulty sleeping Loss of appetite

Expert Tips

If you are prescribed Phesgo 600mg/600mg Injection, or any other medication, it is important to carefully read and understand the warnings and precautions associated with the medication. Patients should be monitored for signs of an allergic reaction, such as rash, itching, or swelling, and should seek immediate medical attention if these symptoms occur. It should be used with caution in patients with severe renal impairment. Talk to the physician if you have heart problems, have had radiotherapy, or have allergic conditions. Use effective birth control during the treatment and at least seven months after the last dose. Always maintain a healthy and balanced diet to support your overall health and well-being.

References

  1. Roche products limited, Electronic medicines compendium (EMC), [Revised on Jan 2022] [ Accessed on 03/05/2023], https://www.medicines.org.uk/emc/files/pil.11989.pdf
  2. zhu Chenjing et al.; Safety and efficacy evaluation of pertuzumab in patients with solid tumors; Medicine; [Published on May 2017]; [Accessed on 03/05/2023] https://journals.lww.com/md-journal/fulltext/2017/05190/safety_and_efficacy_evaluation_of_pertuzumab_in.19.aspx
  3. Sandra M Swain et al; Pertuzumab, Trastuzumab, and docetaxel in HER2-positive metastatic breast cancer; The New England Journal of Medicine; [Published on Feb 2015]; [Accessed on 03/05/203]; https://pubmed.ncbi.nlm.nih.gov/25693012/

Safety Advice

Pregnancy: unsafe It is unknown whether Phesgo 600mg/600mg Injection is excreted in human milk. So breastfeeding women should consult their doctor before taking it.

Lungs: unsafe Patients with pre-existing liver disease or impaired liver function may be at increased risk for the potential side effects of Phesgo 600mg/600mg Injection, including liver toxicity. So patients should discuss it with their healthcare provider before taking it.

Breastfeeding: Consult your doctor Phesgo 600mg/600mg Injection can cause side effects, and the safety of their use in the lungs depends on several factors. Patients should consult their doctor if they have any pre-existing health condition before taking this medication.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS