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Pleumet 100mg Injection

Salt Composition: PEMETREXED

₹3988.00₹4997.02

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Pleumet 100mg Injection contains Pemetrexed, an anticancer medicine that belongs to the antifolate class of drugs. It is used in the treatment of non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma, a cancer affecting the lining of the lungs. Depending on the treatment plan, it may be administered alone or in combination with other chemotherapy medicines such as cisplatin. To help reduce treatment-related side effects, your doctor may prescribe folic acid, vitamin B12, and corticosteroids before and during therapy.

Before each infusion, blood tests are performed to assess your kidney and liver function and ensure your blood cell counts are suitable for treatment. Inform your doctor if you have kidney disease, heart problems, fluid around the lungs, or if you have recently undergone radiotherapy or received any vaccinations. Women should avoid becoming pregnant during treatment and for at least 6 months after the final dose, while men are advised not to father a child during treatment and for 3 months afterward. If you have concerns about fertility, discuss them with your doctor before starting treatment. Pleumet 100mg Injection is not recommended for children and adolescents under 18 years of age.

Uses

Malignant pleural mesothelioma Non-small cell lung carcinoma

How it works

Pleumet 100mg inhibits the mechanism required for cell division and replication by blocking specific enzymes involved in folate metabolism (essential for cell replication) and DNA synthesis, which will prevent the cancer cells from growing and multiplying.

How to Use

Pleumet 100mginjection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Blood infection Severe allergic reaction Breathlessness, intense chest pain or cough with bloody sputum Reduced neutrophil granulocytes (white blood cells) Kidney failure Pharyngitis (a sore throat) Abnormal liver function Common Fatigue Nausea, vomiting, diarrhea Redness, swelling or sores in the mouth Loss of appetite, sensation Reduced hemoglobin level Increased skin pigmentation Watery and inflamed eyes, taste change Fever Muscle weakness Dehydration Constipation Skin rash Hair loss

Expert Tips

Discuss your fertility problem with the doctor since, in men, it is advised not to father a child during and after the 3 months of treatment. So it is advised to get suggestions about fertility concerns. Avoid planning for the pregnancy. If you experience any symptoms mentioned as a side effect, consult your doctor immediately. Notify your doctor immediately if you have undergone any radiotherapy or taken any vaccines and other medications before starting with Pleumet 100mg because it might reduce the effectiveness of this medicine and may cause side effects. Inform your doctor if you have or had any history of heart disease, kidney problems,s or liver problems.

References

  1. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs,7th edition, 2013, 863.
  2. Eagle Pharmaceuticals, US Food and Drug Administration, [ Revised on Feb 2020] [ Accessed on 27 - March - 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/209472s000lbl.pdf
  3. Seacross Pharmaceuticals Ltd, Electronic medicines compendium (emc), [ Accessed on 27 - March - 2023], https://www.medicines.org.uk/emc/files/pil.8887.pdf

Safety Advice

Pregnancy: unsafe Do not take Pleumet 100mg if you are pregnant because it may cause harm to the unborn baby. Consult your doctor before starting the treatment.

Lungs: Consult your doctor Consult your doctor if you experience any symptoms like; shortness of breath, blockage, or inflammation in the lining of the lung while taking Pleumet 100mg.

Breastfeeding: unsafe It is unsafe to breastfeed while taking Pleumet 100mg because it can cause toxicity to the baby. If you are breastfeeding a baby, it has to be discontinued. Please consult your physician for more advice.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS