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Plugo 3mg Tablet
Salt Composition: PLECANATIDE
- Manufacturer: ERIS LIFESCIENCES LIMITED
- Pack Size: 10 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 3MG
- Prescription Required
- Storage: Store at room temperature (20°C to 25°C) in a dry place away from moisture. If a dose is missed, take it as soon as remembered unless it is close to the next dose. Do not double dose. Overdose may result in severe diarrhoea and dehydration. Seek medical help immediately. Keep this medicine out of reach of children
₹1146.00₹1396.88
Inclusive of all taxes
Product Introduction
Plugo 3mg Tablet is an oral medication used to manage certain gastrointestinal conditions. It contains Plecanatide as its active constituent, classified as a guanylate cyclase-C (GC-C) agonist under the therapeutic class of gastrointestinal agents. This medication helps relieve chronic constipation-related disorders by increasing fluid secretion in the intestines, thereby softening stool and promoting regular bowel movements. It is primarily prescribed for chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C) in adults. While generally well-tolerated, Plugo 3mg Tablet comes with specific safety precautions. It is contraindicated in children under six years due to the risk of severe dehydration and should not be used in individuals with known or suspected gastrointestinal obstruction. Patients with a history of severe diarrhoea or hypersensitivity reactions require careful clinical assessment before use.
Uses
FDA-approved uses of Plugo 3mg Tablet include: Chronic idiopathic constipation (CIC) â Persistent constipation with no identifiable cause Irritable bowel syndrome with constipation (IBS-C) â A condition characterised by abdominal pain and constipation
How it works
Plugo 3mg Tablet works by activating specific receptors in the intestines to enhance fluid secretion, which softens stool and facilitates bowel movements. By stimulating the body's natural fluid regulation pathways, it improves stool consistency and promotes regularity. This process also helps reduce abdominal discomfort and bloating. Unlike stimulant laxatives, it does not force bowel contractions but rather supports the body's natural digestion process, making it a more targeted and gentler treatment.
How to Use
Plugo 3mg Tablet is available in oral tablet form and is taken once daily (3 mg dose), with or without food. The tablet should be swallowed whole and not crushed, split, or chewed.
Side Effects
Common Side Effects Diarrhea Bloating Gas Nausea Fatigue Upper respiratory tract infections Serious Side Effects Severe diarrhoea leading to dehydration Severe abdominal pain Allergic reactions (swelling, difficulty breathing, rash)
References
- https://clinicaltrials.gov/study/NCT02387359
- https://go.drugbank.com/drugs/DB13170
- https://pmc.ncbi.nlm.nih.gov/articles/PMC5871240/
- https://pubchem.ncbi.nlm.nih.gov/compound/Plecanatide
Safety Advice
Pregnancy: Consult your doctor The safety of Plugo 3mg Tablet during pregnancy has not been well established. Pregnant women should consult their healthcare provider before using this medication, as it may cause unintended effects on the digestive system.
Lungs: safe There are no direct effects of Plugo 3mg Tablet on lung function. However, individuals with respiratory conditions should be cautious if they experience severe diarrhoea, which may lead to dehydration and impact overall health.
Breastfeeding: Consult your doctor It is unknown whether Plugo 3mg Tablet passes into breast milk. Nursing mothers should use this medication only if the potential benefits outweigh the risks. Consulting a doctor is advisable before starting the treatment.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.