Home › Products › Oncology › Proteoz 2mg Injection
Proteoz 2mg Injection
Salt Composition: BORTEZOMIB
- Manufacturer: ZYDUS CADILA
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 2MG
- Prescription Required
- Storage: Store unopened vials in the refrigerator (2 °C â 8 °C) and protect them from light. Keep this medicine out of sight and reach of children.
₹1898.00₹3163.88
Inclusive of all taxes
Product Introduction
Proteoz 2mg Injection is a chemotherapy medication that belongs to the class of proteasome inhibitors. It contains the active ingredient Bortezomib. It is indicated for the treatment of multiple myeloma and mantle cell lymphoma. Multiple myeloma refers to malignant progression of plasma cells in the bone marrow. Mantle cell lymphoma is a less common cancer affecting the lymph nodes. This medication is used concurrently with other chemotherapy medicines including pegylated liposomal doxorubicin, rituximab, cyclophosphamide, doxorubicin, dexamethasone, prednisolone, or thalidomide in patients with newly diagnosed disease who are ineligible for blood stem cell transplant. Common side effects associated with Proteoz 2mg Injection include pneumonia, loss of appetite, sensory changes including tingling and burning sensation, nausea, vomiting, diarrhoea, mouth ulcers, constipation, muscle and bone pain, hair loss, fever, infections, itching, redness, dehydration, and gastrointestinal problems. Inform your physician if these side effects occur or persist. Inform your doctor of any allergy to Proteoz 2mg Injection or its ingredients. Do not use this medication if you have severe lung or cardiac problems. Before starting treatment, inform your physician if you have neuropathy (nerve malfunction), cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome, gastrointestinal disorders, thrombocytopenia (low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities occurring during cancer treatment), or hepatic disorders. Inform your doctor if you have diabetes, as this injection can affect blood glucose levels.
Uses
Treatment of multiple myeloma and mantle cell lymphoma.
How it works
Proteoz 2mg Injection Injection works by exerting a toxic effect on cancer cells. It inhibits the 26S proteasome and blocks a major cell signaling pathway. This inhibition of the signaling pathway makes the cancer cells sensitive to chemotherapy. This medicine also enhances the build-up of a protein and minimizes cancer cell growth and multiplication.
How to Use
Proteoz 2mg Injection is administered intravenously in your vein or subcutaneously under the skin. This injection should be given by a qualified healthcare professional experienced in the use of cytotoxic medications. Do not self-administer.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Muscle cramps Confusion, visual disturbances, seizures, and headache Breathlessness Swelling of feet Changes in heartbeat High blood pressure Fainting and tiredness Cough and chest tightness Common Pneumonia Loss of appetite Sensitivity, tingling and burning sensation of the skin Nausea, vomiting, and diarrhea Mouth ulcers Constipation Muscle and bone pain Hair loss Fever Reduction in blood cell count Reduced kidney function Shivering Infections Itching and redness Dehydration Stomach problems Difficulty sleeping, anxiety, mood swings, depressed mood
Expert Tips
It is advised that both men and women must use an effective contraception method during treatment and three months afterward. Treatment with Proteoz 2mg Injection can commonly cause a decrease in the number of red and white blood cells and platelets in your blood. Therefore, you will have to take regular blood tests before and during your treatment with bortezomib to check your blood cell counts regularly. Pregnant women should not handle this Injection as it contains cytotoxic agents. Using gloves and protective clothing is recommended to prevent skin contact.
References
- STADA, Electronic Medicines Compendium (EMC), [Revised on Nov 2021] [Accessed on 30 Nov 2022], https://www.medicines.org.uk/emc/files/pil.10201.pdf
- Takeda Pharmaceuticals U.S.A., Inc., [Revised on Aug 2022] [Accessed on 30 Nov 2022], https://www.velcade.com/files/pdfs/VELCADE_PRESCRIBING_INFORMATION.pdf
- Edward Chu, Cancer Chemotherapy, Langeâs Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
- KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
- H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidsonâs Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056
Safety Advice
Pregnancy: unsafe Proteoz 2mg Injection is unsafe to use during pregnancy unless clearly necessary. Both women of childbearing potential and men must use an effective contraception method during and three months after treatment.
Lungs: Consult your doctor It is unknown whether Proteoz 2mg Injection can be given to lung failure patients. Please consult your physician if you have any lung diseases.
Breastfeeding: unsafe Proteoz 2mg Injection is unsafe to use during breastfeeding. Please discuss with your physician when it is safe to restart breastfeeding after this treatment.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.