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Psien 500mg Tablet

Salt Composition: MYCOPHENOLATE MOFETIL

₹725.00₹864.30

Inclusive of all taxes

Categories: Cardiology

Conditions: Transplant

Product Introduction

Psien 500mg Tablet is an immunosuppressant containing the active ingredient Mycophenolate mofetil. It belongs to the inosine monophosphate dehydrogenase (IMPDH) inhibitor category. This medicine is used to prevent organ rejection in patients who have received an organ transplant (such as kidney, heart, or liver transplantation). It is prescribed as part of combination therapy that includes other immunosuppressive drugs.

This drug is contraindicated during pregnancy due to the risk of birth defects and miscarriage. It should not be advised in pregnant women unless there are no relevant alternatives and the potential benefits outweigh the risks. Women of childbearing age are advised to use effective contraception while taking this tablet to prevent pregnancy.

Live vaccines should not be administered while a patient is taking Psien 500mg Tablet due to reduced vaccine effectiveness and the risk of infection. Individuals taking this drug should not donate blood during treatment and for at least six weeks after stopping treatment, to ensure the medication has been adequately cleared from the body before blood donation.

Do not take this medicine if you are allergic to the drug or any other ingredients. Inform your doctor of liver or heart disease before initiating treatment. As this drug reduces the body's immune defences, it can increase the chance of skin cancer. Patients must take precautions to limit exposure to sunlight and ultraviolet (UV) light.

Seek medical attention immediately if you develop any bruising under the skin, fever, unexplained tiredness, dizziness, yellowing of the skin or eyes, vision impairment, reduced urine output, or seizures after taking this medicine.

Psien 500mg Tablet is an immunosuppressive medication. It may affect the infant's developing immune system and should be avoided during breastfeeding. In some cases, alternative medications with a more favourable safety profile during breastfeeding may be considered.

Uses

Prevent organ transplant rejections.

How it works

Psien 500mg Tablet works by inhibiting the enzyme inosine monophosphate dehydrogenase (IMPDH) and reducing the production of guanosine nucleotides. MMF specifically affects the proliferation of activated T and B lymphocytes. These lymphocytes are key players in the immune response that can lead to the rejection of a transplanted organ.

How to Use

It is an orally available prescription drug. Your physician will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Always take Psien 500mg Tablet as prescribed by your doctor. Do not open, crush, break, or chew the medicine.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Infections, fever, or sore throat Unusual bleeding or bruising Low blood cell count Severe allergic reactions Common Higher risk of developing lymphoma and other cancers Nausea, abdominal pain Diarrhea Constipation Loss of appetite Shortness of breath Weight loss Increased heartbeat Headache Blood pressure problem Anaemia

Expert Tips

It is necessary to take the prescribed dose exactly as instructed by your doctor. Inform your doctor about all the medications (prescription, over-the-counter, and herbal) you are taking, as they can interact with this drug. If you plan to conceive or suspect you might be pregnant while taking Psien 500mg Tablet, it is important to consult your doctor immediately. They may suggest switching to alternative medications that are safer during pregnancy or adjusting your treatment plan.

References

  1. Roche Products Limited, European Medicine Consortium (EMC), [Revised on April 2022],[Accessed on 25/05/2023], https://www.medicines.org.uk/emc/files/pil.1103.pdf
  2. Genentech USA, Inc., [ Revised on Oct 2021] [ Accessed on 25/05/2023], https://www.gene.com/download/pdf/cellcept_prescribing.pdf
  3. S.E. Marshall, Immunological Factors in Disease, Davidson's Principles and Practice of Medicine, 22nd Edition, 2014, 71-96.
  4. KD Tripathi, Immunosuppressant Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019,.937-945.
  5. Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Inflammation, Immunomodulation, and Hematopoiesis, 12th Edition, 2011, 1014.

Safety Advice

Pregnancy: unsafe Psien 500mg Tablet is known to have harmful effects on the developing fetus and is generally not prescribed for use during pregnancy unless the benefits outweigh the risks.

Lungs: Consult your doctor Psien 500mg Tablet should be cautiously administered in patients with lung diseases. Dose adjustments are necessary. Inform your physician if you have lung problems before initiating the therapy.

Breastfeeding: unsafe Psien 500mg Tablet is not recommended for breastfeeding mothers because small amounts of the drug can pass into the mother's milk and affect the nursing baby.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS