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Pyrimethamine 25mg Tablet

Salt Composition: PYRIMETHAMINE

₹36.00₹45.00

Inclusive of all taxes

Categories: Infectious Disease

Conditions: Antibacterials

Product Introduction

Pyrimethamine 25mg Tablet contains pyrimethamine, an antiparasitic medicine belonging to the antiprotozoal class. It is used in combination with other antibiotics to treat blood infections caused by the parasite toxoplasma. These infections can affect the brain and other parts of the body in patients with compromised immune systems, such as those with AIDS or HIV infection. It is also used to treat malarial infections.

Do not take Pyrimethamine 25mg Tablet if you are allergic to pyrimethamine or any other ingredients in the tablet, or if you are pregnant or breastfeeding. This tablet is not recommended in children under five years of age.

Inform your physician if you have kidney or liver problems, anaemia, or seizures. This medicine will always be given to you with a vitamin supplement. Do not forget to take your vitamin supplements.

Uses

Toxoplasmosis Acute malaria

How it works

Pyrimethamine 25mg Tablet binds to and reversibly inhibits the protozoal enzyme and selectively blocks its conversion, which is essential for DNA synthesis and cell proliferation.

How to Use

It is an orally available prescription drug. Your doctor will decide the dose and duration of Pyrimethamine 25mg Tablet based on the disease condition and other factors such as body weight and age. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with a glass of water.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Severe skin reactions Low platelet counts Common Skin rash

Expert Tips

Take all of the medicine and complete the course of therapy even if you feel better after the first few doses. Do not take extra dose or medicine to make up for a missed dose. Inform your doctor if you drink alcohol. This medicine may make you bleed, bruise, or catch infections more easily. Take precautions to prevent the illness. Take this medicine as prescribed by your doctor. Take this medicine with food to decrease nausea and vomiting. Do not skip the medicine or change the dose without consulting the doctor. Common side effects like nausea, vomiting, and loss of appetite.

References

  1. Daraprim Tablets - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published February 2023. Accessed May 9, 2023. http://www.medicines.org.uk/emc/product/938/smpc
  2. DARAPRIM ® (Pyrimethamine) 25-Mg Scored Tablets. Accessed May 9, 2023. https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/08578slr016_daraprim_lbl.pdf
  3. Philip J. Rosenthal, Antiprotozoal Drugs, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 917-937.
  4. D.H. Dockrell, S. Sundar, B.J. Angus, R.P. Hobson, Infectious disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 293-386.

Safety Advice

Pregnancy: unsafe Do not take Pyrimethamine 25mg Tablet if you are in your first trimester because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment.

Lungs: Consult your doctor It is unknown whether Pyrimethamine 25mg Tablet is safe to be administer in patients with lung diseases. Inform your physician if you have any lung diseases before initiating the therapy.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Pyrimethamine 25mg Tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS