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R-Thrombo 1500000IU Injection
Salt Composition: STREPTOKINASE
- Manufacturer: BHARAT SERUMS & VACCINES LTD
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 1500000IU
- Prescription Required
- Storage: Store at room temperature, between 2°C to 8°C Keep away from moisture, heat, and light. It should not be frozen. Keep away from children and pets.
₹795.00₹2001.56
Inclusive of all taxes
Product Introduction
R-thrombo 1500000IU contains the active ingredient Streptokinase. It is a thrombolytic medication used in the treatment of thromboembolic conditions. It is indicated for deep vein thrombosis, a condition in which blood clots form in the deep veins, typically in the legs. This medication is used to treat pulmonary embolism, which occurs when a blood clot travels to the lungs and obstructs blood flow. In certain cases, it is used to treat arterial thrombosis, such as those that may cause ischaemic strokes. R-thrombo 1500000IU is used to maintain patency of dialysis fistulas or grafts, which are artificial vascular connections between an artery and a vein created in patients with kidney failure requiring dialysis.
Patients with known hypersensitivity or allergic reaction to R-thrombo 1500000IU or any components of the medication should not use R-thrombo 1500000IU. Do not use this medication in the presence of active internal bleeding, such as gastrointestinal bleeding or recent surgery. Patients with a history of haemorrhagic stroke should not use this medication. Do not use this medication if you have severe renal dysfunction. Elderly patients should consult a healthcare provider due to the higher risk of bleeding associated with age-related changes in blood vessels and other medical conditions. R-thrombo 1500000IU is generally not recommended for use in paediatric populations because safety and efficacy in children have not been adequately studied.
Uses
R-thrombo 1500000IU is used in the following: Myocardial Infarction (heart attack) Deep vein thrombosis (DVT) Pulmonary embolism Arterial clots Peripheral arterial disease Thrombosis in dialysis fistulas/grafts
How it works
R-thrombo 1500000IU operates as a thrombolytic agent by interacting with plasminogen, a precursor protein in the blood. Through its binding, It triggers plasminogen's conversion into plasmin, an active enzyme that dismantles fibrin, the structural framework of blood clots, leading to their dissolution. Promoting this clot breakdown restores blood flow by eliminating blockages in blood vessels, which is essential for preventing tissue damage and related complications.
How to Use
R-thrombo 1500000IU is administered through the intravenous (IV) route or intracoronory. It may also be delivered through an arterial catheter for more localized treatment. Healthcare professionals perform administration following prescribed dosages and guidelines.
Side Effects
R-thrombo 1500000IU causes some side effects like all medications, although not everyone will experience them. Serious Bleeding Allergic Reactions Hypotension (Low Blood Pressure) Fever and Chills Common Bleeding at Injection Site Nausea and Vomiting Fever Allergic Skin Reactions Minor Drop in Blood Pressure Flushing
Expert Tips
Monitor for signs of allergic reactions, including rash, itching, swelling, and difficulty breathing. Discontinue R-thrombo 1500000IU and seek medical attention immediately if any allergic symptoms occur. Use with caution in individuals with a history of bleeding disorders, recent surgery, ulcers, or other conditions that might increase bleeding risk. Monitor blood pressure during administration and address any hypotensive episodes. Follow the prescribed dosage as directed by your healthcare provider. Individuals with severe liver or kidney impairment should talk to healthcare providers to assess their condition and determine the appropriate course of action. Use this medication with caution in individuals who have recently undergone surgery, or had significant trauma.
References
- KD Tripathi, Essentials of Medical Pharmacology, Drugs affecting Coagulation, bleeding, and thrombosis, 7th edition, 2013, 626.
- Tetris Pharma Ltd, Electronic medicines compendium (emc), [Revised on 18th Dec 2021] [ Accessed on 25th 2023], https://www.medicines.org.uk/emc/product/13114/smpc#gref
- Adinarayana Kunamneni, Thaer Taleb Abed Abdelghani, Poluri Ellaiah; streptokinase--the drug of choice for thrombolytic therapy; Journal of Thrombosis and Thrombolysis; Published on Feb 2007; Accessed on 25/08/2023; https://pubmed.ncbi.nlm.nih.gov/17111203/
Safety Advice
Pregnancy: unsafe R-thrombo 1500000IU is unsafe during pregnancy due to potential risks to the developing fetus.
Lungs: Consult your doctor If you have preexisting lung conditions, informing your healthcare provider before starting R-thrombo 1500000IU is advisable.
Breastfeeding: unsafe It is unknown whether R-thrombo 1500000IU is excreted in human milk. Always consult a healthcare provider before taking this medication.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.