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Rabies Antiserum Injection

Salt Composition: RABIES ANTISERUM

₹488.00₹609.38

Inclusive of all taxes

Categories: Others

Conditions: Injections & Vaccine

Product Introduction

Rabies antiserum injection contains rabies antiserum as its active component and belongs to the immunoglobulin drug class. It is also referred to as rabies immune-globulin or rabies immune serum. This medical treatment is used to prevent rabies development in individuals exposed to the rabies virus. A key advantage of rabies antiserum injection is that it provides immediate passive immunity against the rabies virus. It forms a crucial part of post-exposure prophylaxis (PEP) for individuals who have been bitten, scratched, or otherwise exposed to a potentially rabid animal. By neutralising the rabies virus at the exposure site, it can help prevent the virus from entering the nervous system and progressing to symptomatic rabies.

Individuals with a known history of severe allergic reactions (anaphylaxis) to any component of rabies antiserum injection or to any previous rabies vaccination should not receive rabies antiserum injection. If an individual has previously completed a full course of rabies vaccination (pre-exposure prophylaxis), they may not require rabies antiserum injection in the event of subsequent exposure, as their immune system should already have developed an antibody response to the rabies virus. Use in older age and paediatric populations requires healthcare provider consultation.

Uses

Rabies antiserum injection is used in the following: Post-exposure prophylaxis of rabies infection.

How it works

Rabies antiserum injection provides immediate protection through pre-formed antibodies that neutralize the rabies virus at the exposure site. This prevents the virus from entering nerve cells and allows the individual's immune system to generate antibodies through vaccination, ultimately preventing rabies infection.

How to Use

Rabies antiserum injection is typically administered through the intramuscular (IM) route. It is injected directly into the muscle, usually at or near the site of potential rabies exposure, to provide immediate passive immunity against the rabies virus. Always consult with a healthcare professional for proper administration guidance based on the specific circumstances of exposure.

Side Effects

Rabies antiserum injection causes some side effects like all medications, although not everyone will experience them. Serious Severe allergic reactions Common Allergic reactions Neurological side effects Other serious reactions

Expert Tips

Before taking Rabies antiserum injection, inform your healthcare provider if you have any allergies, especially to medications used in rabies treatment, as severe allergies may require special consideration. Additionally, if you have conditions that weaken your immune system, like HIV, or if you are taking medications that suppress immunity, it's important to know that the rabies vaccine may not work as effectively, so discuss this with your healthcare provider. If you are pregnant or breastfeeding, you must talk with your healthcare provider before starting rabies treatments. They will assess the risks and benefits to determine the best course of action for your specific situation. If you have liver or kidney issues, inform your healthcare provider, as this may impact your treatment plan. After receiving rabies treatment, it's advisable to avoid alcohol consumption for a period. If you experience any pain or discomfort at the injection site, it's best not to drive immediately after the treatment. If you have clotting disorders or multiple bite wounds, exercise extra caution, as there may be a higher risk of bleeding at the injection sites. Always consult your healthcare provider for personalized advice, as rabies is a serious concern, and timely and appropriate treatment is essential to ensure your safety.

References

  1. Thomas Moulenat et al., Purified Vero Cell Rabies Vaccine (PVRV, Verorab®): A Systematic Review of Intradermal Use Between 1985 and 2019, Trop. Med. Infect. Dis., 2020, 5, 40, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157209/pdf/tropicalmed-05-00040.pdf
  2. KD Tripathi, Vaccines, Antisera and lmmuneglobulins, Essentials of Medical Pharmacology, 8th Edition, 2019, 978-986.
  3. Kedrion Biopharma Inc., US Food and Drug Administration, [Revised on 2020] [Accessed on 11th September 2020], https://www.fda.gov/media/106795/downloa

Safety Advice

Pregnancy: Consult your doctor It is important to consult a healthcare provider before using Rabies antiserum injection, as its safety during pregnancy is unknown. The benefits of preventing rabies must outweigh any potential risks to the fetus.

Lungs: Consult your doctor Rabies antiserum injection and vaccination are typically safe for individuals with lung conditions. If you have respiratory issues or lung conditions, consult a healthcare provider before using it.

Breastfeeding: Consult your doctor The antibodies are not significantly excreted in breast milk in significant amounts. Breastfeeding women should consult a health care provider before using Rabies antiserum injection.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS