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Rabipur Vaccine

Salt Composition: RABIES ANTISERUM

₹269.00₹336.76

Inclusive of all taxes

Categories: Others

Conditions: Injections & Vaccine

Product Introduction

Rabipur Vaccine contains rabies immune globulin (rabies antiserum), an immunoglobulin used to prevent rabies development in individuals exposed to the rabies virus. It provides immediate passive immunity against rabies and forms a crucial component of post-exposure prophylaxis (PEP) for persons bitten, scratched, or otherwise exposed to potentially rabid animals. By neutralising the rabies virus at the exposure site, it can help prevent the virus from entering the nervous system and progressing to symptomatic rabies.

Rabipur Vaccine should not be administered to individuals with a known history of severe allergic reactions (anaphylaxis) to any component of the rabies antiserum or to any previous rabies vaccination. Individuals who have previously completed a full course of rabies vaccination (pre-exposure prophylaxis) may not require it in the event of subsequent exposure, as their immune system should already have developed an antibody response to the rabies virus. Use in elderly patients or children requires healthcare provider guidance.

Uses

Rabipur Vaccine is used in the following: Post-exposure prophylaxis of rabies infection

How it works

The Rabipur Vaccine works by providing immediate protection through pre-formed antibodies that neutralise the rabies virus at the exposure site. This prevents the virus from entering nerve cells and allows the individual's immune system to generate antibodies through vaccination, ultimately preventing rabies infection.

How to Use

Rabipur Vaccine is typically administered through the intramuscular (IM) route. It is injected directly into the muscle, usually at or near the site of potential rabies exposure, to provide immediate passive immunity against the rabies virus. Always consult with a healthcare professional for proper administration guidance based on the specific circumstances of exposure.

Side Effects

Rabipur Vaccine causes some side effects like all medications, although not everyone will experience them. Serious side effects of Rabipur Vaccine are: Severe allergic reactions Common side effects of Rabipur Vaccine are: Allergic reactions Neurological side effects Other serious reactions

Expert Tips

Before taking the Rabipur vaccine, inform your healthcare provider if you have any allergies, especially regarding medications used in rabies treatment, as severe allergies may require special consideration. Additionally, if you have conditions that weaken your immune system, like HIV, or if you are taking medications that suppress immunity, it's important to know that the rabies vaccine may not work as effectively, so discuss this with your healthcare provider. If you are pregnant or breastfeeding, you must talk with your healthcare provider before starting rabies treatments. They will assess the risks and benefits to determine the best course of action for your specific situation. If you have liver or kidney issues, inform your healthcare provider, as this may impact your treatment plan. After receiving rabies treatment, it's advisable to avoid alcohol consumption for a period. If you experience any pain or discomfort at the injection site, it's best not to drive immediately after the treatment. If you have clotting disorders or multiple bite wounds, exercise extra caution, as there may be a higher risk of bleeding at the injection sites. Always consult your healthcare provider for personalised advice, as rabies is a serious concern, and timely and appropriate treatment is essential to ensure your safety.

References

  1. Thomas Moulenat et al., Purified Vero Cell Rabies Vaccine (PVRV, Verorab®): A Systematic Review of Intradermal Use Between 1985 and 2019, Trop. Med. Infect. Dis., 2020, 5, 40, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157209/pdf/tropicalmed-05-00040.pdf
  2. KD Tripathi, Vaccines, Antisera and lmmuneglobulins, Essentials of Medical Pharmacology, 8th Edition, 2019, 978-986.
  3. Kedrion Biopharma Inc., US Food and Drug Administration, [Revised on 2020] [Accessed on 11th September 2020], https://www.fda.gov/media/106795/downloa

Safety Advice

Pregnancy: Consult your doctor It is unknown what the safety of Rabies antiserum is. It is important to consult a healthcare provider before using Rabipur Vaccine, as its safety during pregnancy is unknown. The benefits of preventing rabies must outweigh any potential risks to the fetus.

Lungs: Consult your doctor Rabipur Vaccine and vaccination are typically safe for individuals with lung conditions. If you have respiratory issues or lung conditions, consult a healthcare provider before using it.

Breastfeeding: Consult your doctor The antibodies are not significantly excreted in breast milk in significant amounts. Breastfeeding women should consult a healthcare provider before using Rabipur Vaccine.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS