Rasbase 1.5mg Injection

Rasbase 1.5mg Injection is an antihyperuricemic drug belonging to the category of uricolytic agents, containing the active ingredient rasburicase. It is used in the treatment of acute hyperuricemia in patients receiving chemotherapy. When cancer cells break down, they can release large amounts of uric acid into the bloodstream. This can cause hyperuricemia, which can lead to kidney damage and other health problems. This medicine can also be used to prevent or treat hyperuricemia in patients with tumour lysis syndrome, a condition in which a large number of cancer cells die within a short period.

In patients with G6PD deficiency, rasburicase can trigger haemolysis (destruction of red blood cells) by generating reactive oxygen species that damage red blood cells. As a result, rasburicase is generally contraindicated in patients with G6PD deficiency. If you are diagnosed with this deficiency, inform your physician before taking this medicine because you will be more likely to experience severe haemolytic anaemia or methemoglobinemia (an abnormal form of haemoglobin).

Children undergoing chemotherapy for leukaemia, lymphoma, or solid tumour malignancies are at risk of developing hyperuricemia, which can lead to kidney damage, seizures, and other complications. This drug helps treat hyperuricemia by rapidly reducing the levels of uric acid in the blood. It is important to closely monitor children receiving rasburicase for any signs of allergic reactions, haemolysis (breakdown of red blood cells), or any other side effects. Inform your healthcare provider if you have kidney or liver disease, vision problems, or lung problems. Your healthcare provider will check regular blood tests to prevent complications. Avoid consuming alcohol as it may cause dizziness.

Rasbase 1.5mg Injection is unsafe to use during pregnancy as it causes harm to an unborn fetus. Your healthcare practitioner will conduct a pregnancy test before you start treatment with Rasbase 1.5mg Injection. Discuss with your doctor effective birth control methods and utilise them for at least two weeks following the last dose.

Treat high uric acid levels in chemotherapy

It works by converting uric acid into allantoin, a more soluble compound that can be easily excreted by the kidneys. This reduces the levels of uric acid in the blood and prevents the development of hyperuricemia.

The medicine will be administered to you by a healthcare professional in a hospital setting. Rasbase is given as an injection into a vein (intravenous infusion) over a period of 30 minutes, once a day for up to 5 days. The dose, route of administration, and frequency will be decided by your doctor based on your disease condition and other factors.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Swelling of face, lips, tongue Wheezing and breathing problems Common Nausea, vomiting Fever Swelling Anxiety Headache Abdominal pain Constipation Diarrhea Low phosphate levels in the blood High levels of liver enzymes in the blood Rashes

Avoid driving and operating heavy machinery if you feel tired or weak during this treatment. Certain activities or conditions that can trigger gout attacks, such as fasting, rapid weight loss, and stress, should also be avoided while taking Rasbase. Foods that are high in purines should be avoided, such as red meat, organ meats, and some seafood, which can increase uric acid levels and reduce the effectiveness of Rasbase. It is important to avoid or limit consumption of these foods while taking Rasbase. Dehydration can reduce the effectiveness of the medication and increase the risk of side effects, so it is necessary to drink plenty of fluids, especially water, while taking this medicine. Smoking can cause oxidative stress in the body, which can lead to an increase in uric acid levels. It is advised to avoid smoking or using tobacco products while undergoing treatment with Rasbase.