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Refra 2.5mg Tablet
Salt Composition: MIDODRINE
- Manufacturer: SANFEGAN BIOTECH PVT LTD
- Pack Size: 15 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 2.5MG
- Prescription Required
- Storage: Refra 2.5mg Tablet should be stored at room temperature between 68°F to 77°F (20°C to 25°C). Keep in the original package. Keep away from light, moisture, and heat. Keep away from children and pets. Avoid taking double doses for missed doses.
₹518.00₹575.44
Inclusive of all taxes
Product Introduction
Refra 2.5 mg Tablet contains the active ingredient Midodrine and is prescribed for treating low blood pressure (hypotension). It belongs to the class of medicines called alpha-1 adrenergic agonists, which work by constricting blood vessels and increasing blood pressure. The dosage prescribed depends on the patient's medical condition, blood pressure readings, and response to treatment. Always follow your doctor's prescribed schedule. The tablet should be swallowed whole with water, with or without food, and ideally during daytime hours to reduce the risk of high blood pressure while lying down. Both Refra and Midotab contain midodrine as the active ingredient but may differ in brand formulation, availability, and cost. Patients should not switch brands without consulting their doctor. Several substitutes are available that also contain midodrine, but a change in brand or formulation should only be done under medical supervision. For use in kidney disease, caution is advised, especially in patients with severe kidney impairment or end-stage renal disease, as dose adjustments may be required to prevent drug accumulation.
Uses
Refra tablet uses in Treatment of orthostatic hypotension (low BP when a person stands up from a seated or lying)
How it works
The therapeutic effect of Refra 2.5mg Tablet is to increase blood pressure in individuals with low blood pressure or orthostatic hypotension. Acting as an alpha-1 adrenergic agonist and constricting blood vessels, helps to raise peripheral vascular resistance and improve blood flow to vital organs, particularly the brain. This medication enhances blood pressure and offers a therapeutic benefit by improving quality of life, functional capacity, and cognitive function in individuals with orthostatic hypotension.
How to Use
Refra 2.5mg Tablet is taken orally as a Tablet 10'S and should be taken with or without food. The Tablet 10'Ss should be swallowed whole with water and not crushed, chewed, or opened. The dosage and duration of treatment will depend on the individual's condition and response to the medication and should be determined by a healthcare provider.
Side Effects
Refra 2.5mg Tablet can cause side effects like all medications, although not everyone who takes it will experience them. Refra side effects include Serious: Chest pain or tightness Rapid or irregular heartbeat Severe dizziness or lightheadedness Shortness of breath or difficulty breathing Severe headache Blurred vision or other vision changes Fainting or loss of consciousness Signs of an allergic reaction (e.g., hives, swelling, difficulty breathing) Common: Scalp tingling or piloerection (goosebumps) Itching or rash Abdominal discomfort or pain Nausea Headache High blood pressure (especially when lying down)
Expert Tips
Use Refra 2.5mg Tablet with caution in patients with heart problems, urinary retention, kidney disease, or a history of pheochromocytoma or peripheral vascular disease. Avoid use in individuals with uncontrolled hypertension or severe heart conditions such as unstable angina, congestive heart failure, or recent heart attack. Do not discontinue the medication abruptly; follow your doctor’s guidance when stopping treatment. Pregnancy and breastfeeding should be avoided during treatment unless approved by a doctor. Monitor pediatric and elderly patients closely, and report any allergic or hypersensitivity reactions immediately.
References
- Goodman & Gilmanâs, The Pharmacological Basics of Therapeutics, Adrenergic agonists and antagonists, 12th edition, 2011,294-295.
- Tillomed Laboratories Ltd, Electronic medicines compendium (EMC), [Revised on 16 November 2022], [Accessed on 30th May 2023], https://www.medicines.org.uk/emc/files/pil.12496.pdf
- Shrine US, US Food and Drug Administration, [Revised on Jan 2017] [Accessed on 30th May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/019815s010lbl.pdf
Safety Advice
Pregnancy: Consult your doctor The safety of using Refra 2.5mg Tablet during pregnancy has not been established. Limited studies are available regarding the use of this medication in pregnant women, so it is recommended to use caution and consult a doctor before considering its use during pregnancy.
Lungs: Consult your doctor If you have a history of lung or respiratory disorders, it is important to consult your healthcare provider before taking Refra 2.5mg Tablet.
Breastfeeding: Consult your doctor It is unknown whether Refra 2.5mg Tablet is excreted in milk. So it is better to consult a healthcare provider if you are a breastfeeding mother before taking this medication.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.