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Regdual 40mg Tablet
Salt Composition: REGORAFENIB
- Manufacturer: INTAS PHARMACEUTICALS LTD
- Pack Size: 28 TABLET(s) IN A BOTTLE
- Dosage Form: TABLET
- Strength: 40MG
- Prescription Required
- Storage: Keep this medicine out of sight and reach of children. Store at room temperature between 20°C to 25°C.
₹3188.00₹3750.00
Inclusive of all taxes
Product Introduction
Regdual 40mg Tablet is a targeted therapy containing regorafenib as the active ingredient. It is indicated for the treatment of colorectal cancer, rectal cancer, hepatocellular carcinoma, and gastrointestinal stromal tumours (GIST), which occur in the stomach and bowel. Cancer is characterised by uncontrolled and abnormal cell multiplication. Inform your doctor if you have liver disease, active infection, bleeding disorders, gastrointestinal conditions, chest pain, cardiac disease, hypertension, persistent headache, seizures, or if you have recently undergone or are scheduled for surgical intervention prior to commencing this medication. Regdual 40mg Tablet is not recommended for paediatric and adolescent patients. Avoid consumption of grapefruit juice during treatment, as it may alter the pharmacokinetic profile of this medicine. Employ effective contraceptive measures throughout treatment and for a minimum of eight weeks following the final dose. Inform your doctor if you follow a sodium-restricted diet, as Regdual 40mg Tablet contains sodium.
Uses
Colorectal cancer has started to spread to other parts of the body Gastrointestinal stromal tumors (GIST) (a type of stomach and bowel cancer) Liver cancer in adult patients who have already undergone treatment with Sorafenib (anticancer medicine)
How it works
Regdual 40mg Tablet binds to tyrosine kinase receptors and inhibits the VEGF (vascular endothelial growth factor) and EGFR (epidermal growth factor receptor) receptors on the cell surface. By binding to these receptors, this medication blocks an important pathway that promotes cell division. This helps to prevent the growth and multiplication of cancer cells.
How to Use
Always take this medicine exactly as your doctor has told you. Swallow the tablets whole with water. Do not crush or chew the tablets. Avoid drinking grapefruit juice while taking this medicine.
Side Effects
Side Effects are unwanted symptoms caused by medicines. Although all medicines cause side effects, not everyone gets them. Severe : Liver problems (yellowish discoloration of skin and whites of the eyes, dark urine, confusion) Bleeding Infection (high fever, cough with or without sputum, pain when urinating, unusual vaginal discharge, shortness of breath) Stomach and bowel problems (severe stomach pain, blood in vomit, red or black stools) Common: Low blood cell count Decreased appetite, weight loss Nausea, vomiting High blood pressure Voice changes Diarrhea Dry mouth, painful tongue, mouth sores Changes in liver function Weakness, lack of energy Pain, redness, blisters and swelling of palms of the hands or soles of the feet Dehydration Hair loss, dry skin Headache Heartburn Low levels of potassium, phosphate, calcium, sodium or magnesium in blood Shaking Numbness, tingling Taste disorders Muscle spasms Abnormal clotting condition Protein in the urine
Expert Tips
Before starting Regdual 40mg Tablet, inform your doctor if you have any liver conditions, infections, bleeding problems, heart diseases, high blood pressure, stomach or bowel issues, or are undergoing surgery. This medication is not recommended for children and adolescents. Avoid consuming grapefruit juice while on Regdual, as it may reduce the drug's effectiveness. Women who are pregnant, planning pregnancy, or breastfeeding should avoid using this medicine due to the potential harm to the developing baby. Always consult your doctor for guidance.
References
- Bayer AG; Electronic Medicines Compendium; [Revised:2019] [Accessed:29/Apr:2021] https://www.medicines.org.uk/emc/files/pil.1263.pdf
- TJ Ettrich et al; Regorafenib; [Revised:2014] [Accessed:29/Apr/2021] https://pubmed.ncbi.nlm.nih.gov/24756792/
- Dirk Strumberg; Regorafenib for cancer; [Revised:2012] [Accessed:29/Apr/2021] https://pubmed.ncbi.nlm.nih.gov/22577890/
- Bayer HealthCare Pharmaceuticals Inc; US Food And Drug Administration; [Revised:2012] [Accessed:29/Apr/2021] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/203085lbl.pdf
Safety Advice
Pregnancy: unsafe This medicine is not safe to be used in pregnancy. Consult with your doctor for advice.
Lungs: Consult your doctor Regdual 40mg Tablet may cause lung-related side effects, such as interstitial lung disease. It should be used with caution in patients with pre-existing lung conditions. Consult with your doctor for advice.
Breastfeeding: unsafe It is not recommended to breastfeed while taking Regdual 40mg Tablets. Consult with your doctor for advice
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.