Rinodel 40mg Injection

Rinodel 40mg Injection is an anti-cancer medicine belonging to the class of cytostatics. It contains the active ingredient Irinotecan hydrochloride trihydrate. It is indicated for advanced colon cancer and rectal cancer in adults. Treatment may be given as monotherapy or in combination with other chemotherapeutic agents. Colon and rectal cancer occurs more frequently in age groups above 50 and is associated with genetic and environmental factors. Myelosuppression (bone marrow suppression leading to decreased levels of red blood cells, white blood cells, and platelets) and diarrhoea are the most commonly reported adverse effects. Other frequent side effects of Rinodel 40mg Injection include nausea, vomiting, abdominal pain, constipation, anaemia, pain, fatigue, fever, infections including sepsis, abnormal bilirubin levels, hair loss, and weight loss. Inform your doctor if these side effects occur or persist. Notify your physician if you have an allergy to Rinodel 40mg Injection or any of its ingredients. Before starting treatment, inform your physician if you have liver problems or jaundice, kidney or heart problems, asthma, high blood pressure or high cholesterol, or severe diarrhoea. If you smoke or have previously received radiation therapy, report this to your healthcare provider. Inform your healthcare provider if you are taking other medicines, herbs, or supplements. Effective contraception by both males and females during treatment is important to prevent pregnancy. Your physician will perform blood tests before and during treatment to monitor the effects of the medicine on blood counts and blood chemistry.

Treatment of metastatic cancer of the colon and rectum (large intestine).

Rinodel 40mg Injection works by converting its active metabolite with the help of liver enzymes and inhibits the Topoisomerase I enzyme. This causes damage to the DNA synthesis and its replication, thus preventing the cancer cells from growing and spreading.

Take this medicine exactly as prescribed. Your healthcare professional administers it into your vein. Do not self-administer. Your physician will recommend a DNA test before taking this medicine. The dose depends on your age, size, and medical condition.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Early and late diarrhea Allergic reactions Kidney impairment Lung problems Low levels of RBC, WBC, and platelets in the blood Common: Nausea, vomiting, abdominal pain Constipation Diarrhea Anemia Pain Fatigue Fever, infections including sepsis Abnormal bilirubin levels Hair loss Weight loss

Diarrhoea is the first sign of Rinodel 40mg Injection. It may be serious if diarrhoea starts more than 24 hours after administration of this medication. It should be treated immediately and kept under close supervision. If left untreated, it could lead to dehydration and serious chemical imbalances, which can be life-threatening. Try to avoid laxatives and stool softeners while taking this medicine. Drink large amounts of water and rehydration fluids immediately. Take an antidiarrheal treatment like loperamide.