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Rituxirel RN 500mg Injection
Salt Composition: RITUXIMAB
- Manufacturer: RELIANCE LIFE SCIENCES PVT LTD
- Pack Size: 1 VIAL(s) OF 50ML
- Dosage Form: INJECTION
- Strength: 500MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Store in the refrigerator at 2°C to 8°C . Do not freeze. Keep out of reach of children and pets. If you miss a scheduled dose, inform your doctor as soon as possible.
₹6103.00₹40688.00
Inclusive of all taxes
Product Introduction
Rituxirel RN 500mg Injection contains rituximab, an anti-CD20 monoclonal antibody. It is used in adults to treat various types of blood cancers including non-Hodgkin's lymphoma (NHL) and chronic lymphocytic leukaemia (CLL). It also manages autoimmune diseases such as rheumatoid arthritis (RA), when used with methotrexate, as well as granulomatosis with polyangiitis and microscopic polyangiitis (inflammatory conditions affecting blood vessels). Additionally, it is prescribed for pemphigus vulgaris, a rare condition causing painful skin blisters and sores in the mouth, throat, and other areas. This injection works by targeting specific white blood cells called B-lymphocytes, which may grow abnormally in cancer or behave incorrectly in autoimmune conditions. Rituxirel RN 500mg is administered under the supervision of a qualified healthcare professional. It is not recommended if you are allergic to rituximab, have severe infections, or have a weakened immune system. Before starting treatment, inform your doctor if you have heart or lung problems, or a history of hepatitis B infection, as the virus can reactivate during treatment. Pregnant and breastfeeding women should avoid this injection. Effective contraception is advised during treatment and for at least 12 months after the last dose. Common side effects may include low red blood cells, infections, itchy skin, swelling, diarrhoea, or changes in blood pressure. Serious side effects such as infusion-related reactions, chest pain, or difficulty breathing should be reported to your doctor immediately.
Uses
Non-hodgkinâs lymphoma (NHL) Chronic lymphocytic leukemia (CLL) Rheumatoid Arthritis Granulomatosis with polyangiitis or microscopic polyangiitis Pemphigus vulgaris
How it works
Rituxirel RN 500mg Injection targets CD20 proteins found on B-cells, a type of white blood cell. In cancer, it helps kill these abnormal cells. In autoimmune diseases, it reduces inflammation by lowering the number of B-cells that wrongly attack the body’s own tissues. This helps improve symptoms and slow disease progression.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Swelling in the face and body Diarrhea and nausea Itchy skin Anemia Muscle spasm Headache Urinary tract infection Fever, chills, and shivering Inflammation of nasal cavities Cough, sore throat Loss of hair Serious Increased or decreased blood pressure Chest pain Hypersensitivity reactions Hepatitis B viral infection Memory loss, trouble thinking, difficulty in walking
Expert Tips
Avoid live vaccines before, during, and after treatment until your doctor advises it’s safe. Always inform your doctor about your full medical history, especially if you've had heart, liver, or lung conditions. If you're planning a pregnancy, wait at least 12 months after the last dose. Report any new or recurring infections, unusual tiredness, or unexplained symptoms to your healthcare provider.
References
- HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021). Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/103705s5464lbl.pdf [Accessed 9 Mar. 2023].
- ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020). Available at: https://www.ema.europa.eu/en/documents/product-information/mabthera-epar-product-information_en.pdf [Accessed 9 Mar. 2023].
- Ahmed A. Negm & Daniel E. Furst, Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout, Lange's Basic & Clinical Pharmacology, 14th Edition, 2018, 642-666
Safety Advice
Pregnancy: unsafe Rituxirel RN 500mg injection is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.
Lungs: Consult your doctor It is unknown whether Rituxirel RN 500mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Rituxirel RN 500mg injection because the medicine passes into the breast milk in small amounts and may harm your baby.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.