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Romstim 125mcg Injection

Salt Composition: ROMIPLOSTIM

₹1440.00₹1800.00

Inclusive of all taxes

Categories: Hematology

Conditions: Blood Disorder

Product Introduction

Romstim 125mcg Injection belongs to the platelet-stimulating agent category and contains Romiplostim. It is used to treat immune primary thrombocytopenia (ITP), a condition in which the body's immune system mistakenly destroys its own platelets, leading to low platelet counts. This medicine is mainly prescribed for adults and children aged 18 years and above when other treatments have not worked. It is generally recommended when immunoglobulins, corticosteroids, or splenectomy have failed to improve platelet levels. This treatment purpose applies to lower-strength formulations as well, which are used for the same therapeutic indication with dose adjustments based on platelet response.

This drug is contraindicated in individuals with known hypersensitivity to Romiplostim or medicines produced using E. coli-based DNA technology. Before receiving this injection, inform your physician if you have liver disorders, cancer, a recent surgery, smoking habits, or if you are taking birth control pills. These factors can influence the medication's effectiveness and safety, helping your physician determine if adjustments are necessary.

During treatment, your physician will conduct regular blood tests to check for abnormalities that may indicate bone marrow changes. Romiplostim has been associated with significant bone marrow alterations, so ongoing monitoring is essential. Based on test results, your doctor may decide whether to continue or discontinue therapy.

The medication is not recommended during pregnancy unless clearly advised by your doctor. If pregnant, planning pregnancy, or suspecting pregnancy, you must inform your physician. Since it is unknown whether the drug passes into breast milk, breastfeeding should be avoided.

Awareness of potential side effects is important, which may include headache, dizziness, bone pain, or injection-site reactions. If Romstim is not suitable, your doctor may recommend alternative agents that provide similar therapeutic effects.

Uses

Treatment of immune thrombocytopenia (ITP)

How it works

Romstim 125mcg Injection works by stimulating the production of platelets in the bone marrow. It binds to and activates the thrombopoietin receptor, which promotes the development and maturation of platelets. This helps to increase the platelet count in individuals with ITP.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Loss of response Progression of Myelodysplastic Syndromes Thromboembolic complications Leukemia Higher risk of blood clots Common Headache, dizziness Allergic reaction Upper respiratory tract infection Joint pain, muscle pain Indigestion Sleeping trouble Tingling or numbness of the feet or hands Abdominal pain, diarrhoea, and indigestion Fever, cough

References

  1. Amgen Limited, Electronic medicines compendium (EMC), [ Revised on Oct 2021] [ Accessed on 14th July 2023], https://www.medicines.org.uk/emc/files/pil.567.pdf
  2. Amgen Inc, US Food and Drug Administration, [ Revised on Dec 2018] [Accessed on 14th July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/125268s163lbl.pdf
  3. Douglas B.cines et al.; Safety and efficacy of romiplostim in splenectomized patients with primary immune thrombocytopenia; Haematologica; Published on August 2017; Accessed on 14th July 2023; https://www.haematologica.org/article/view/8154

Safety Advice

Pregnancy: Unsafe Romstim 125mcg Injection is not recommended for pregnant patients unless specifically indicated by your doctor. Inform your physician if you are pregnant, suspecting, or planning for a pregnancy before initiating the treatment.

Lungs: Consult Your Doctor It is unknown whether Romstim 125mcg Injection is safe for patients with lung problems. Inform your physician if you have lung disease before starting the treatment.

Breastfeeding: Consult Your Doctor It is not known whether Romstim 125mcg Injection is present in human milk. Therefore, this drug is not recommended for use while breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS