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Rozel 60mg Injection

Salt Composition: DENOSUMAB

₹8432.00₹14053.13

Inclusive of all taxes

Rozel 60mg Injection

Categories: Rheumatology

Conditions: Arthritis

Product Introduction

Rozel 60mg Injection contains the active ingredient denosumab and is used to treat osteoporosis and to prevent bone complications in patients with cancer. Rozel injection is indicated for treating osteoporosis (to strengthen weakened bones) and managing bone loss related to cancers such as multiple myeloma and bone metastases. Rozel works by inhibiting RANK ligand, a protein involved in bone breakdown. Studies have demonstrated it can increase bone density and reduce fracture risk in postmenopausal women and patients with cancer-related bone loss. The exact Rozel injection dosage and administration schedule are determined by your oncologist or specialist, as it is administered in a clinic setting and requires monitoring. When comparing Rozel with Prolia, both are denosumab-based products; differences are primarily in brand name, approved indications and cost.

Uses

Rozel 60mg Injection is used in the treatment of the following condition: Osteoporosis Bone loss due to hormonal therapy in breast or prostate cancer Multiple myeloma (cancer affects plasma cells in the bone marrow) Bone metastases (cancer that spreads to bone)

How it works

Rozel 60mg Injection has therapeutic effects that include reducing fracture risk, increasing bone mineral density, and improving overall bone health. By inhibiting bone resorption through its action on RANK ligands, this medication helps to strengthen bones and decrease the likelihood of fractures in individuals with osteoporosis or those at high risk. It also increases bone mineral density, an important marker of bone strength. These therapeutic effects contribute to improved bone health and a reduced risk of fractures, ultimately enhancing the quality of life for patients.

Side Effects

Rozel 60mg Injection can cause side effects like all medications, although not everyone who takes it will experience them. Rozel injection side effects are Serious: Osteonecrosis of the jaw (severe necrosis or death of jaw cells) Atypical femoral fractures Hypocalcemia (low blood calcium levels) Common: Injection site reactions Back pain Musculoskeletal pain Infections Abdominal pain Headache Hypophosphatemia (low blood phosphate levels)

Expert Tips

Attend all scheduled appointments and follow-up visits to monitor treatment response and manage side effects. Tell your doctor about your full medical history, especially previous infections, liver disease, and kidney disease. Inform your healthcare provider about any allergies or past hypersensitivity reactions. Seek immediate medical attention if you experience severe allergic reactions or any other serious side effects. Rozel 60mg Injection may affect calcium levels — have your calcium checked regularly and ensure adequate calcium and vitamin D intake as advised by your doctor.

References

  1. Amgen Ltd, Electronic medicines compendium (EMC), [ Revised on 13th May 2023], [ Accessed on 31st May 2023], https://www.medicines.org.uk/emc/files/pil.568.pdf
  2. Amgen Manufacturing Limited, US Food and Drug Administration, [ Revised on November 2010] [ Accessed on 31st May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/125320s007lbl.pdf
  3. Amgen Manufacturing Limited, US Food and Drug Administration, [ Revised on November 2022] [ Accessed on 31st May 2023], https://www.fda.gov/media/163378/download

Safety Advice

Pregnancy: Consult your doctor The safety of using Rozel 60mg Injection during pregnancy has not been established. Limited studies are available regarding the use of this medication in pregnant women, so it is recommended to use caution and consult a doctor before considering its use during pregnancy.

Lungs: Consult your doctor If you have a lung or respiratory disorders history, it is important to consult your healthcare provider before taking Rozel 60mg Injection.

Breastfeeding: Consult your doctor Whether Rozel 60mg Injection is excreted in milk is unknown. So it is better to consult a healthcare provider if you are a breastfeeding mother before taking this medication.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS