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Ruparib 300mg Tablet
Salt Composition: RUCAPARIB
- Manufacturer: EMCURE PHARMACEUTICALS LTD
- Pack Size: 60 TABLET(s) IN A BOTTLE
- Dosage Form: TABLET
- Strength: 300MG
- Prescription Required
- Storage: Store at 20°C to 25°C Protect the medicine from light and excessive moisture. Keep the medicine out of reach of children and pets If you forgot to take the tablet, take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.
₹38323.00₹47903.05
Inclusive of all taxes
Product Introduction
Ruparib 300mg tablet contains the active ingredient rucaparib, an anti-cancer medicine belonging to the class of PARP (poly ADP-ribose polymerase) inhibitors. It is used to maintain the response to other treatments for certain types of ovarian cancer, fallopian tube cancer, and primary peritoneal cancer that has recurred in adults who have previously achieved complete or partial response to chemotherapy. It is also indicated for certain types of cancer in patients with specific BRCA gene changes who have received at least two prior chemotherapy treatments. Ruparib 300mg tablet is indicated as maintenance therapy immediately following chemotherapy that has caused tumour shrinkage.
Do not take Ruparib 300mg tablet if you are allergic to rucaparib or any of the ingredients. This medication can cause low blood counts; your healthcare professional will advise blood tests before treatment commences and monthly during treatment. Inform your doctor if you experience nausea, vomiting, diarrhoea, or abdominal pain during treatment, as this medicine may affect your stomach or bowels. Ruparib 300mg tablet should not be given to children under 18 years of age. Notify your physician if you are pregnant, breastfeeding, or planning pregnancy during treatment with this medicine. Women of reproductive potential should use effective contraception during treatment.
Uses
Ovarian cancer Fallopian tube cancer Primary peritoneal cancer Prostate cancer
How it works
Ruparib 300mg tablet is an inhibitor of poly Adenosine diphosphate-ribose polymerase enzymes, including PARP-1, PARP-2, and PARP-3, which play a role in DNA repair. It blocks an enzyme that repairs damaged DNA in the cancer cells, resulting in their death.
How to Use
It is an orally available prescription drug. Your doctor will decide the dose and duration of Ruparib 300mg tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Rash Constipation Decrease in appetite Diarrhea, indigestion Nausea, vomiting Changes in the blood count Shortness of breath Tiredness Serious Severe anemia Hypersensitivity reactions Sepsis (blood infection) Pneumonia
Expert Tips
You may get sunburn easily during treatment with Ruparib 300mg tablet. Keep out of direct sunlight and wear protective clothing that covers your head, arms, and legs. Use sunscreen and lip balm with a sun protection factor (SPF) after consulting your doctor. If you vomit after taking the medicine, do not take an extra dose. Take your next dose at the regular time. Do not stop taking this medicine without talking to your doctor. Your doctor may do lab tests to check the therapy's effectiveness or monitor the unwanted side effects.
References
- Rubraca 250mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. [revised on 2022] [cited 2023 Apr 11]. Available from: https://www.medicines.org.uk/emc/product/10027/smpc
- HIGHLIGHTS OF PRESCRIBING INFORMATION - Rucaparib. [revised on 2018] [cited 2023 Apr 11]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/209115s003lbl.pdf
- Shirley M. Rucaparib: A Review in Ovarian Cancer. Targeted Oncology. [2019 Apr 1] [cited 2022 Oct 15];14(2):237â46. Available from: https://pubmed.ncbi.nlm.nih.gov/30830551/
Safety Advice
Pregnancy: unsafe Do not take Ruparib 300mg tablet if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for 6 months after the last dose.
Lungs: Consult your doctor It is unknown whether Ruparib 300mg tablet is safe to be administer in patients with lung diseases. Inform your physician if you have any lung diseases before initiating the therapy.
Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Ruparib 300mg tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.