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Sacuval 50mg Tablet
Salt Composition: SACUBITRIL,VALSARTAN
- Manufacturer: ALKEM LABORATORIES LTD
- Pack Size: 10 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 50MG
- Prescription Required
- Storage: Do not store above 25°C). Store in the original package to protect from light. keep the injection away from the reach of children and pets.
₹181.00₹213.25
Inclusive of all taxes
Product Introduction
Sacuval 50mg Tablet contains the active ingredients Sacubitril and Valsartan. It belongs to the class of cardiovascular medicines known as angiotensin receptor-neprilysin inhibitors (ARNIs). This medicine is used to treat certain types of chronic heart failure in adults. It is often prescribed along with other heart medications to help reduce the risk of hospitalization and death in adults with specific forms of heart failure.
Do not take Sacuval 50mg Tablet if you are allergic to Sacubitril, Valsartan, or any of the other ingredients in this medicine. Avoid using this tablet if you currently have or have ever experienced angioedema (swelling of the face, lips, tongue, or throat that may cause breathing difficulty). This medicine should also not be taken if you have diabetes or impaired kidney function and are receiving treatment with a blood pressure-lowering medicine containing Aliskiren. Do not use this tablet if you have severe liver disease or if you are pregnant or breastfeeding. Inform your doctor about any other heart medications you are taking before starting treatment. Also, tell your doctor if you have low blood pressure, severe kidney disease, dehydration, liver problems, hallucinations, or sleep disturbances. The most common side effects of Sacuval 50mg Tablet include low blood pressure (hypotension), increased potassium levels, cough, dizziness, and kidney failure.
Uses
To reduce the risk of cardiovascular death and hospitalization in adults with heart failure.
How it works
Sacubitril is a prodrug metabolized to the active metabolite, which inhibits neprilysin, thereby increasing levels of peptides (such as natriuretic peptides). It works to help control blood volume. Valsartan is an angiotensin receptor blocker that selectively blocks the AT1 receptor and inhibits angiotensin-II-dependent aldosterone release. It works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.
How to Use
Always take this medicine exactly as your doctor or pharmacist has told you. Your physician will decide the dose and duration of the treatment based on your disease severity and other factors. Swallow the tablets with a glass of water. You can take Sacuval 50mg Tablet with or without food. Do not crush, chew, or split the tablets.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Low blood pressure Increased potassium levels Dizziness Serious Kidney damage Angioedema (swelling of the face, lips, tongue and throat, and difficulties in breathing)
Expert Tips
It is advisable to take your medicine at the same time each day. However, if you forget to take a dose, you should take the next one at the scheduled time. Do not take a double dose to make up for a forgotten tablet. Inform your physician if you have kidney problems before initiating the therapy. This medicine could lower your blood pressure too much, especially when you first use it or if you are dehydrated. Stand or sit up slowly if you feel dizzy or lightheaded. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
References
- Novartis Pharmaceuticals UK Ltd, Electronic Medicines Compendium(EMC), [Revised on June 2023 [Accessed on 14th June 2023], https://www.medicines.org.uk/emc/files/pil.5074.pdf
- Novartis, US Food and Drug Administration, [Revised on February 2021] [Accessed on 14th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/207620s018lbl.pdf
- KD Tripathi, Cardiac Glycosides and Drugs for Heart Failure, Essentials of Medical Pharmacology, 8th Edition, 2019, 556-569.
- Ian A. Reid, Vasoactive Peptides, Langeâs Basic & Clinical Pharmacology, 14th Edition, 2018, 300-320.
Safety Advice
Pregnancy: unsafe Do not take Sacuval 50mg Tablet if you are pregnant because it may cause harm to the unborn baby. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.
Lungs: Consult your doctor It is unknown whether Sacuval 50mg Tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Sacuval 50mg Tablet because the medicine passes into the breast milk in small amounts and may harm your baby.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.