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Samluta 40mg Capsule

Salt Composition: ENZALUTAMIDE

₹4454.00₹25781.25

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Samluta 40mg Capsule

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Samluta 40mg Capsule contains Enzalutamide, an androgen receptor inhibitor used as a targeted therapy. It is prescribed for adults with advanced prostate cancer that no longer responds to surgical or hormonal interventions. This oral anticancer medication works by blocking the effects of male hormones (androgens) that drive the growth of prostate cancer cells. Patients taking Samluta 40mg require regular monitoring through PSA (Prostate-Specific Antigen) blood tests to assess disease progression and treatment response. Liver function tests and complete blood counts are also recommended periodically to track safety during long-term use. This medication may lower the seizure threshold and should be used with caution in individuals with a history of neurological conditions. Avoid grapefruit or grapefruit juice, as it may increase drug levels in the blood. Because of its potential to cause infertility and fetal harm, effective contraception is essential for both men and women during and for at least three months after stopping treatment.

Uses

Used in the treatment of advanced prostate cancer that has not responded to other therapies.

How it works

Samluta 40mg Capsule works by blocking the androgen receptors on prostate cancer cells. These receptors normally allow the hormone dihydrotestosterone (DHT) to stimulate cancer growth. By preventing DHT from binding, the drug disrupts cancer cell signaling, slows disease progression, and reduces tumor proliferation.

Side Effects

Like most cancer treatments, Samluta 40mg may cause some side effects. While not everyone experiences them, it’s important to be aware: Common Side Effects: Fatigue or tiredness Back pain or joint stiffness Headache or difficulty concentrating High blood pressure Constipation or diarrhea Loss of appetite Dry skin or skin rashes Breast swelling in men (gynecomastia) Serious Side Effects: Seizures Allergic reactions Posterior Reversible Encephalopathy Syndrome (PRES) Falls or bone fractures Heart conditions or palpitations Seek immediate medical help if you experience any signs of severe side effects.

References

  1. Astellas Pharma Ltd, [Revised on Oct 2020] [Accessed on 8th Apr 2021], https://www.astellas.us/docs/12a005-enz-wpi.pdf
  2. Astellas Pharma Europe B.V, Electronic Medicines Compendium (EMC), [Revised on May 2021] [Accessed on 12th Nov 2021], https://www.medicines.org.uk/emc/files/pil.10318.pdf
  3. Martín LázaroQuintela et al., Enzalutamide: a new prostate cancer targeted therapy against the androgen receptor, Cancer Treatment Reviews. Mar 2015; 41(3): 247-253 [Accessed on 8th Apr 2021], https://ruc.udc.es/dspace/bitstream/handle/2183/21551/Lzro_Enzlutamide.pdf?sequence=3&isAllowed=y
  4. Marina D. Kaymakcalan and Christy S. Harris, Prostate Cancer, Applied Therapeutics, The Clinical Use Of Drugs, 11th Edition, 2018, 2083-2100.

Safety Advice

Pregnancy: unsafe Though not used by women, exposure during pregnancy can harm the unborn baby. Men with partners of childbearing age must use contraception during and for 3 months after the last dose.

Lungs: Consult your doctor The safety of Samluta in patients with lung diseases has not been established. Report any existing respiratory concerns to your physician.

Breastfeeding: Consult your doctor Samluta is not intended for use in women, especially during lactation. Speak with your doctor if accidental exposure occurs.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS