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Sibofix 200mg Tablet

Salt Composition: RIFAXIMIN

₹189.00₹235.78

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Sibofix 200mg Tablet

Categories: Infectious Disease

Conditions: Antibacterials

Product Introduction

Sibofix 200mg Tablet contains Rifaximin as its active ingredient. It is an antibiotic used to treat traveller’s diarrhoea caused by non-invasive strains of Escherichia coli in adults. It is also prescribed to reduce the recurrence of overt hepatic encephalopathy, a condition involving impaired brain function associated with liver disease. Depending on the patient's condition, Sibofix 200mg Tablet may be used alone or in combination with medicines containing lactulose.

It should also be avoided if you have an intestinal blockage, fever, bloody stools, or have experienced more than eight unformed bowel movements within the past 24 hours. Before starting treatment, inform your doctor if you have liver disease or any other underlying medical condition. This medicine is not recommended for children or adolescents under 18 years of age. Common side effects include headache, swelling of the feet or legs, nausea, dizziness, fatigue, and abdominal bloating. Inform your healthcare provider if you are pregnant or breastfeeding before using this medicine. In case of an accidental overdose, seek immediate medical attention.

Uses

Traveler’s diarrhoea Hepatic encephalopathy

How it works

Sibofix 200mg Tablet acts by binding to the bacterial DNA-dependent RNA polymerase blocking one of the steps in the transcription process. This results in the inhibition of bacterial protein synthesis and consequently inhibits the growth of bacteria.

How to Use

Always use this medicine as exactly as your doctor prescribes. Depending on the condition being treated, your physician decides the dose, dosage, and duration of the treatment. Take the tablet at the same time every day, with or without food. Swallow the tablets with a glass of water. Do not break, crush, or chew the tablets.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Swelling of the legs and feet Abdominal pain Nausea Abdominal swelling Dizziness, headache Tiredness Serious Anemia Allergic reactions

Expert Tips

While taking Sibofix 200mg Tablet, your urine may appear to be reddish. Treatment with this medicine can cause severe diarrhoea. Inform your physician if you have diarrhoea for several weeks. If you forgot to take the tablet, take it as soon as you remember. However, skip the missed dose if it is nearly time for the next dose. Inform your physician if you're taking oral contraceptives (medicines to prevent pregnancy). Your doctor may suggest you take certain tests to monitor the effectiveness and side effects of the therapy.

References

  1. Norgine Pharmaceuticals Limited., Electronic Medicines Compendium (EMC), [Revised on October 2020] [Accessed on June 2023 ], https://www.medicines.org.uk/emc/files/pil.4752.pdf
  2. Norgine Pharmaceuticals Limited., Electronic Medicines Compendium (EMC), [Revised on October 2020] [Accessed on June 2023 ], https://www.medicines.org.uk/emc/files/pil.2976.pdf
  3. Camille E. Beauduy, Lisa G. Winston, Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics & Sterilants, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 895-903.
  4. I.D. Penman, C.W. Lees, Alimentary tract and pancreatic disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 837-920.
  5. Q.M. Anstee, D.E.J. Jones, Liver and biliary tract disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 921-988.

Safety Advice

Pregnancy: unsafe Do not use Sibofix 200mg Tablet during pregnancy because it harms the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment.

Lungs: Consult your doctor It is not known whether Sibofix 200mg Tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Sibofix 200mg Tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS