Home › Products › Infectious Disease › Sofovir 400mg Tablet

Sofovir 400mg Tablet

Salt Composition: SOFOSBUVIR

₹2356.00₹15705.44

Inclusive of all taxes

Sofovir 400mg Tablet

Categories: Infectious Disease

Conditions: Hepatitis

Product Introduction

Sofovir 400mg Tablet contains sofosbuvir as its active component. It is a direct-acting antiviral medication used to treat hepatitis C virus (HCV) infection. This medication is often combined with other antiviral drugs to form a regimen that can effectively eliminate HCV from the body. Sofovir 400mg Tablet has significantly shortened the duration of HCV treatment compared to older therapies. It is effective against multiple genotypes of the hepatitis C virus. This broad-spectrum activity makes it a versatile treatment option that can be used for patients with different HCV genotypes. Patients have generally tolerated this medication well, with few serious side effects reported. Sofovir 400mg Tablet should not be used in individuals with known hypersensitivity or allergic reactions to sofosbuvir or its components. This medication is primarily eliminated through the kidneys. Therefore, individuals with severe renal impairment may require dosage adjustments. It is not approved for use in individuals under the age of 18.

Uses

Treatment of hepatitis C virus (HCV) infection

How it works

Sofovir 400mg Tablet, a direct-acting antiviral medication, exerts a potent therapeutic effect in treating hepatitis C virus (HCV) infections. This medication disrupts the virus's ability to replicate and proliferate within the body by inhibiting the RNA polymerase enzyme necessary for HCV replication. When combined with other antiviral drugs, this targeted action leads to high cure rates, improved treatment outcomes, and shorter treatment durations.

How to Use

Sofovir 400mg Tablet is typically prescribed with other antiviral medications for treating hepatitis C (HCV) infection. This medication is usually taken orally once a day, with or without food. It is recommended to complete the full course of treatment as prescribed, even if symptoms improve, to ensure the best chance of achieving a sustained virologic response (SVR) and curing the HCV infection.

Side Effects

Sofovir 400mg Tablet cause some side effects like all medications, although not everyone will experience them. Serious: Allergic reactions that affect skin and breathing Hepatitis B infection reactivation Bradycardia (slow heartbeat) Common: Fatigue Headache Nausea Insomnia Diarrhea Itching Decreased appetite Rash or skin reactions

Expert Tips

Before starting treatment, inform your healthcare provider if you have a history of hepatitis B, your liver function, HBV DNA levels (an indicator of hepatitis B infection in the blood) will closely monitor during treatment. Be aware of the risk of serious bradycardia when Sofovir 400mg Tablet is combined with Amiodarone, and inform your healthcare provider if you are taking this medication. Any signs of allergic reactions, such as difficulty breathing or swelling, should be reported immediately. Pregnant and breastfeeding individuals should discuss the potential risks and benefits with their healthcare provider. Adhere to the prescribed treatment regimen and attend regular check-ups to monitor treatment response.

References

  1. Gilead Sciences Ltd, Electronic medicines compendium (EMC), [Revised on 15 Nov 2021], [Accessed on 2nd June 2023], https://www.medicines.org.uk/emc/product/12361/pil#gref
  2. Gilead Sciences Ltd, US Food and Drug Administration, [Revised on August 2015],[Accessed on 1st June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/204671s002lbl.pdf

Safety Advice

Pregnancy: Consult your doctor The safety of Sofovir 400mg Tablet use during pregnancy has not been established. If you are pregnant or planning to become pregnant, discussing the potential risks and benefits with your healthcare professional is essential.

Lungs: Consult your doctor Suppose you have a pre-existing lung condition or are concerned about the safety of the Sofovir 400mg Tablet in your lungs. Consulting with your healthcare provider for personalized advice is recommended in that case.

Breastfeeding: Consult your doctor Limited data are available on the safety of Sofovir 400mg Tablet during breastfeeding, and it is important to discuss the potential risks and benefits with a healthcare professional.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS