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Solu Medrol 125mg Injection
Salt Composition: METHYLPREDNISOLONE
- Manufacturer: PFIZER LTD
- Pack Size: 1 VIAL(s) OF 2ML
- Dosage Form: INJECTION
- Strength: 125MG
- Prescription Required
- Storage: Store Solu medrol 125mg injection at controlled room temperature (20°-25°C). Protect from sunlight Keep it out of reach from children and pets.
₹410.00₹499.61
Inclusive of all taxes
Product Introduction
Solu-Medrol 125 mg injection is a glucocorticoid anti-inflammatory agent containing methylprednisolone. It is indicated for inflammatory and allergic conditions affecting the brain (resulting from tumour or meningitis), lungs (resulting from asthma, hypersensitivity, tuberculosis, or aspiration of vomit or gastric contents), gastrointestinal tract, and bowel (Crohn's disease and ulcerative colitis). It is used to treat rheumatic, dermatological, ocular, and endocrine disorders. It is also used for palliative management of malignancies (leukaemia and lymphoma) and reduction of postoperative pain. In higher doses, it is used to manage acute exacerbations of multiple sclerosis. This injection is contraindicated in patients with fungal infections, cerebral oedema due to malaria, traumatic brain injury, or those who have recently received or are scheduled to receive vaccination. Common side effects include headache, visual disturbances, delayed wound healing, and bone weakness. Serious side effects include venous thromboembolism (leg veins and lungs) and peptic ulceration with bleeding. Inform your healthcare provider if these side effects are concerning or persist beyond the expected duration. This medication can increase the risk of certain ocular complications, including posterior subcapsular cataracts and glaucoma. These conditions may result in vision loss if untreated. Additionally, corticosteroids can suppress immune function, increasing susceptibility to secondary ocular infections caused by fungi or viruses. Therefore, corticosteroids should be used at the minimum effective dose for the shortest necessary duration to minimise the risk of these adverse effects. If you experience any change in vision or ocular discomfort during treatment with Solu-Medrol 125 mg injection or any other corticosteroid, inform your doctor immediately. Your healthcare provider will monitor blood pressure, electrolyte levels, and renal function closely during corticosteroid therapy to prevent adverse effects. Corticosteroids increase urinary calcium excretion, which can lead to osteoporosis and elevated fracture risk with prolonged use. Your doctor will prescribe calcium and vitamin D supplementation to support bone health during corticosteroid therapy. Inform your physician of all medications currently being taken, including herbal medicines and supplements, prior to receiving this injection.
Uses
Treatment of allergic conditions Rheumatic, blood, skin, eye, and endocrine disorders Leukemia and lymphomas (palliative management) Pain related to surgery (organ transplants) Multiple sclerosis Ulcerative colitis
How it works
It works by binding to glucocorticoid receptors and inhibits the production of substances (such as prostaglandins) that lead to inflammation and allergies.
How to Use
Solu medrol 125mg injection will be administered to you by a healthcare professional in a hospital setting. This injection will be given intramuscularly or intravenously into a vein in your arm. Do not self-administer this medicine. It is available in two strengths 40 mg/mL and 80 mg/mL. The dose of the injection will be decided by your doctor based on your disease condition and other factors.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Allergic reactions (wheezing, swelling of face, difficulty breathing) Stomach pain spreading to your back, accompanied by vomiting and loss of consciousness Bleeding ulcers Infections Blood clots in the lung (chest pain, coughing up blood, breathlessness) Raised pressure within the skull (lack of energy, drowsiness) Blood clots in the leg vein Common High blood pressure, headache Swelling Ulcers Vision problems Poor wound healing Round or moon-shaped face Slow growth in infants, children, and adolescents Muscle and bone weakness Feeling depressed or high, difficulty in thinking, memory loss Acne, bruising Thinning of skin
Expert Tips
Solu medrol 125mg injection can cause harm to a developing fetus or nursing baby, so it is important to notify your physician if you are pregnant, breastfeeding, or planning to have a baby. Grapefruit juice and grapefruit should be avoided by individuals taking this drug. This medicine can cause several side effects related to electrolyte and fluid balance. When given in large doses, these medications can increase blood pressure, cause salt and water retention, and increase the excretion of potassium. These effects are less likely to occur with prolonged use or high doses. To prevent these side effects, dietary salt restriction and potassium supplementation may be necessary.
References
- Pfizer Limited, Electronic medicines compendium (emc), [ Revised on April 2021] [ Accessed on 7th July 2021], https://www.medicines.org.uk/emc/files/pil.1550.pdf
- Pfizer, US Food and Drug Administration, [ Revised on Oct 2011] [ Accessed on 7th July 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/011856s103s104lbl.pdf
- Medrol, Food and Drug Administration, (Accessed on March 20, 2023), https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/011153s075lbl.pdf
- Goodman & Gilmanâs, The Pharmacological Basis of Therapeutics, ACTH, adrenal steroids, and pharmacology of the adrenal cortex, 12th edition, 2011, 1231.
- KD Tripathi, Essentials of Medical Pharmacology, Corticosteroids, 7th edition, 2013, 288.
Safety Advice
Pregnancy: unsafe Solu medrol 125mg injection is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment. A dose adjustment is suggested.
Lungs: Consult your doctor It is not known whether Solu medrol 125mg injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe Breastfeeding is not recommended in patients administered with a Solu medrol 125mg injection because it may harm your baby. Do not breastfeed during the treatment.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.