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Solu Medrol 1gm Injection

Salt Composition: METHYLPREDNISOLONE

₹1726.00₹1918.13

Inclusive of all taxes

Solu Medrol 1gm Injection

Categories: Rheumatology

Conditions: Arthritis

Product Introduction

Solu Medrol 1 gm Injection is an anti-inflammatory glucocorticoid containing methylprednisolone. It is used to treat inflammatory and allergic conditions affecting the brain (caused by tumour or meningitis), lungs (caused by asthma, hypersensitivity, tuberculosis, or aspiration of vomit or gastric contents), gut, and bowel (Crohn's disease and ulcerative colitis). Solu Medrol 1 gm is also used for rheumatic, skin, eye, and endocrine disorders. It is indicated for palliative management of certain cancers (leukaemia and lymphoma) and reduction of postoperative pain. At higher doses, it is used to treat acute exacerbations of multiple sclerosis symptoms. This injection should not be used if you have a fungal infection, cerebral oedema due to malaria, traumatic brain injury, or have recently received or are scheduled to receive any vaccination. Common side effects include headache, vision problems, impaired wound healing, and bone weakness. Serious side effects may include venous thromboembolism in leg and pulmonary veins, and bleeding peptic ulcers. Inform your doctor if these side effects concern you or persist beyond the expected duration.

Solu Medrol Injection can increase the risk of certain ocular complications, including posterior subcapsular cataracts and glaucoma. These conditions may result in vision loss if untreated. Additionally, corticosteroids can suppress immune function, increasing susceptibility to secondary ocular infections caused by fungi or viruses. Use corticosteroids at the lowest effective dose for the shortest duration to minimise these risks. Report any vision changes or eye discomfort to your doctor immediately. Your healthcare provider will monitor blood pressure, electrolyte levels, and renal function during corticosteroid therapy. Corticosteroids increase urinary calcium excretion, which may lead to osteoporosis and elevated fracture risk with prolonged use. Your doctor may prescribe calcium and vitamin D supplementation to support bone health. Inform your doctor of all medications, including herbal preparations and supplements, before receiving this injection.

Uses

Solu-medrol injection uses are: Treatment of allergic conditions Rheumatic, blood, skin, eye, and endocrine disorders Leukemia and lymphomas (palliative management) Pain related to surgery (organ transplants) Multiple sclerosis Ulcerative colitis

How it works

Solu medrol 1 gram IV works by binding to glucocorticoid receptors and inhibits the production of substances (such as prostaglandins) that lead to inflammation and allergies.

How to Use

Solu medrol 1gm injection will be administered to you by a healthcare professional in a hospital setting. This injection will be given intramuscularly or intravenously into a vein in your arm. Do not self-administer this medicine. It is available in two strengths 40 mg/mL and 80 mg/mL. The dose of the injection will be decided by your doctor based on your disease condition and other factors.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Solu medrol injection side effects are: Serious Allergic reactions (wheezing, swelling of face, difficulty breathing) Stomach pain spreading to your back, accompanied by vomiting and loss of consciousness Bleeding ulcers Infections Blood clots in the lung (chest pain, coughing up blood, breathlessness) Raised pressure within the skull (lack of energy, drowsiness) Blood clots in the leg vein Common High blood pressure, headache Swelling Ulcers Vision problems Poor wound healing Round or moon-shaped face Slow growth in infants, children, and adolescents Muscle and bone weakness Feeling depressed or high, difficulty in thinking, memory loss Acne, bruising Thinning of skin

Expert Tips

Solu medrol 1gm injection can cause harm to a developing fetus or nursing baby, so it is important to notify your physician if you are pregnant, breastfeeding, or planning to have a baby. Grapefruit juice and grapefruit should be avoided by individuals taking this drug. This medicine can cause several side effects related to electrolyte and fluid balance. When given in large doses, these medications can increase blood pressure, cause salt and water retention, and increase the excretion of potassium. These effects are less likely to occur with prolonged use or high doses. To prevent these side effects, dietary salt restriction and potassium supplementation may be necessary.

References

  1. Pfizer Limited, Electronic medicines compendium (emc), [ Revised on April 2021] [ Accessed on 7th July 2021], https://www.medicines.org.uk/emc/files/pil.1550.pdf
  2. Pfizer, US Food and Drug Administration, [ Revised on Oct 2011] [ Accessed on 7th July 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/011856s103s104lbl.pdf
  3. Medrol, Food and Drug Administration, (Accessed on March 20, 2023), https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/011153s075lbl.pdf
  4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, ACTH, adrenal steroids, and pharmacology of the adrenal cortex, 12th edition, 2011, 1231.
  5. KD Tripathi, Essentials of Medical Pharmacology, Corticosteroids, 7th edition, 2013, 288.

Safety Advice

Pregnancy: unsafe Solu medrol 1gm injection is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment. A dose adjustment is suggested.

Lungs: Consult your doctor It is not known whether Solu medrol 1gm injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients administered with a Solu medrol 1gm injection because it may harm your baby. Do not breastfeed during the treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS