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Somastin 3000mcg Injection

Salt Composition: SOMATOSTATIN

₹700.00₹875.00

Inclusive of all taxes

Somastin 3000mcg Injection

Categories: Endocrinology

Conditions: Others

Product Introduction

Somastin 3000mcg Injection contains somatostatin, a synthetic octreotide compound. Octreotide is a substance naturally present in the human body that suppresses the effects of certain hormones, including growth hormone. The injection is indicated for patients with acromegaly (excessive growth hormone production leading to enlargement of hands, feet, and facial features, joint pain, and related symptoms) who are not candidates for surgery, radiation therapy, or other medications. It is used to manage diarrhoea and flushing in patients with carcinoid tumours (slow-growing tumours that release endogenous substances causing symptomatology) and vasoactive intestinal peptide-secreting adenomas (VIP-omas, pancreatic tumours that release endogenous substances causing symptomatology). The injection prevents complications following pancreatic surgery. It is also indicated to arrest bleeding and prevent re-bleeding from ruptured gastro-oesophageal varices in patients with chronic liver disease. Somastin 3000mcg Injection treats patients with pituitary tumours producing elevated thyroid-stimulating hormone (TSH) when surgery or radiotherapy are unsuitable or ineffective, and following radiotherapy to bridge the interval until radiotherapy achieves full effectiveness.

Uses

To treat acromegaly Relieve symptoms associated with some tumors of the GI tract To prevent complications following surgery of the pancreas gland To treat pituitary tumors that produce too much TSH

How it works

Somatostatin, a neuropeptide agent, inhibits growth hormone, glucagon, and insulin more effectively than the natural hormone. The drug also reduces growth hormone and IGF-I (somatomedin C) in acromegaly, inhibits gallbladder contractions, reduces bile secretion, and suppresses thyroid stimulating hormone (TSH) secretion.

How to Use

Always use this medicine as exactly prescribed by your doctor. Depending on the condition being treated, an infusion of Somatostatin is given by either subcutaneous (under the skin) injection, intramuscularly (into the muscle of the buttocks), or intravenous (into a vein). If you are prescribed a subcutaneous injection, your doctor or other healthcare professional will explain how to inject the medicine under the skin.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Increased heart rate Changes in heart rhythm Increased or decreased blood sugar levels Changes in thyroid levels Vitamin B12 deficiency Gall stones Common Diarrhea, flatulence Abdominal pain Back pain Tiredness

Expert Tips

Regularly check blood sugar levels and inform your physician if you notice any changes such as increased or decreased blood sugar level. Female patients of reproductive potential use an alternative non-hormonal method of contraception, such as condoms, when the oral form of this medicine is used. Somatostatin 3000mcg Injection is given as a shot under your skin, into a muscle, or into a vein, based on your condition. This medicine may improve fertility in women and can cause unwanted pregnancies. Talk to your doctor if you have any concerns.

References

  1. SANDOSTATIN LAR 10 mg powder and solvent for suspension for injection, Electronic Medicines Compendium (EMC), [Revised May 2022], [Accessed on 5th July 2023], https://www.medicines.org.uk/emc/files/pil.1038.pdf
  2. Highlights Of Prescribing Information - Somatostatin Injection. Access.fda.gov. [Revised 2019 Apr] [Accessed on 5th July 2023] https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021008s043lbl.pdf
  3. Biocon, [Accessed on 5th July 2023], https://www.biocon.com/docs/prescribing_information/ccd/zomator_pi.pdf
  4. KD Tripathi, Essentials of Medical Pharmacology, Hormone and related drugs, 7th edition, 2013,237-239.

Safety Advice

Pregnancy: Consult your doctor Somatostatin 3000mcg Injection will only be given during pregnancy if needed. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment.

Lungs: Consult your doctor It is unknown whether Somatostatin 3000mcg Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Somatostatin 3000mcg Injection because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS