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Somatin 3000 Injection

Salt Composition: SOMATOSTATIN

₹1383.00₹1729.00

Inclusive of all taxes

Somatin 3000 Injection

Categories: Endocrinology

Conditions: Others

Product Introduction

Somatin 3000 Injection contains the active substance somatostatin. It is a synthetic compound of octreotide, a substance naturally found in the human body that inhibits the effects of certain hormones, such as growth hormone. It is used to reduce the amount of growth hormone produced by patients with acromegaly (a condition in which the body produces too much growth hormone, causing enlargement of the hands, feet, and facial features, joint pain, and other symptoms) who cannot be treated with surgery, radiation, or another medication. It is also used to control diarrhoea and flushing caused by carcinoid tumours (slow-growing tumours that release natural substances that can cause symptoms) and vasoactive intestinal peptide-secreting adenomas (VIP-omas, tumours that form in the pancreas and release natural substances that can cause symptoms). It is used to prevent complications following surgery of the pancreas gland. It is also indicated to stop bleeding and to protect from re-bleeding from ruptured gastro-oesophageal varices in patients with chronic liver disease. Somatin 3000 Injection is used to treat patients with pituitary tumours that produce too much thyroid-stimulating hormone (TSH) when other types of treatment (surgery or radiotherapy) are not suitable or have not worked and after radiotherapy, to cover the interim period until the radiotherapy becomes fully effective. Do not use this medicine if you are allergic to Somatin 3000 Injection or any of the other ingredients of this medicine. Inform your physician if you have gallstones, high or low blood sugar levels, vitamin B12 deficiency, and liver diseases. This drug may lower your heart rate, and very high doses can cause abnormal heart rhythm, so your doctor may monitor your heart function regularly during treatment. Inform your physician if you are pregnant or breastfeeding before initiating treatment.

Uses

To treat acromegaly Relieve symptoms associated with some tumors of the GI tract To prevent complications following surgery of the pancreas gland To treat pituitary tumors that produce too much TSH

How it works

Somatin 3000 Injection, a neuropeptide agent, inhibits growth hormone, glucagon, and insulin more effectively than the natural hormone. The drug also reduces growth hormone and IGF-I (somatomedin C) in acromegaly, inhibits gallbladder contractions, reduces bile secretion, and suppresses thyroid stimulating hormone (TSH) secretion.

How to Use

Always use this medicine as exactly prescribed by your doctor. Depending on the condition being treated, an infusion of Somatin 3000 Injection is given by either subcutaneous (under the skin) injection, intramuscularly (into the muscle of the buttocks), or intravenous (into a vein). If you are prescribed a subcutaneous injection, your doctor or other healthcare professional will explain how to inject the medicine under the skin.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Increased heart rate Changes in heart rhythm Increased or decreased blood sugar levels Changes in thyroid levels Vitamin B12 deficiency Gall stones Common Diarrhea, flatulence Abdominal pain Back pain Tiredness Headache, nausea

Expert Tips

Regularly check blood sugar levels and inform your physician if you notice any changes such as increased or decreased blood sugar level. Female patients of reproductive potential use an alternative non-hormonal method of contraception, such as condoms, when the oral form of this medicine is used. Somatin 3000 Injection is given as a shot under your skin, into a muscle, or into a vein, based on your condition. This medicine may improve fertility in women and can cause unwanted pregnancies. Talk to your doctor if you have any concerns.

References

  1. SANDOSTATIN LAR 10 mg powder and solvent for suspension for injection, Electronic Medicines Compendium (EMC), [Revised May 2022], [Accessed on 5th July 2023], https://www.medicines.org.uk/emc/files/pil.1038.pdf
  2. Highlights Of Prescribing Information - Somatostatin Injection. Access.fda.gov. [Revised 2019 Apr] [Accessed on 5th July 2023] https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021008s043lbl.pdf
  3. Biocon, [Accessed on 5th July 2023], https://www.biocon.com/docs/prescribing_information/ccd/zomator_pi.pdf
  4. KD Tripathi, Essentials of Medical Pharmacology, Hormone and related drugs, 7th edition, 2013,237-239.
  5. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Hormone and hormone antagonists, 12th edition, 2011, 1113.

Safety Advice

Pregnancy: Consult your doctor Somatin 3000 Injection will only be given during pregnancy if needed. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment.

Lungs: Consult your doctor It is unknown whether Somatin 3000 Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Somatin 3000 Injection because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS