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Sorafeb 200mg Tablet 30's
Salt Composition: SORAFENIB
- Manufacturer: NEON LABORATORIES LTD
- Pack Size: 30 TABLET(s) IN A BOTTLE
- Dosage Form: TABLET
- Strength: 200MG
- Prescription Required
- Storage: Store Sorafeb 200mg Tablet 30's in the original package at room temperature (20°C to 25°C). Keep it out of reach of children.
₹1424.00₹2190.00
Inclusive of all taxes
Product Introduction
Sorafeb 200mg Tablet 30's is a multikinase inhibitor containing sorafenib and belongs to the class of cancer medications. It is indicated for treatment of advanced renal cell carcinoma, hepatocellular carcinoma, and thyroid cancer.
Do not take Sorafeb 200mg Tablet 30's if you are allergic to sorafenib or any other ingredients in the medicine. Inform your doctor immediately if you develop skin rashes, heart problems, chest pain, bleeding problems, or high blood pressure, or if you have had or are about to undergo surgery.
This medication is not recommended for use in children and adolescents. Patients with diabetes require frequent monitoring of blood sugar levels, as dosage adjustment of anti-diabetic medications may be necessary to reduce hypoglycaemia risk.
Your doctor will monitor liver function tests and fluid and electrolyte balance to identify and manage potential side effects promptly.
Do not use this medication during pregnancy as it may harm the fetus. Women of reproductive age should undergo pregnancy testing before starting treatment. Continue birth control for at least six months after completing treatment.
Avoid breastfeeding during treatment as this medication may affect your baby's growth and development. This treatment may affect fertility in both men and women; consult your doctor before starting therapy.
Inform your doctor of all medicines you are taking, including prescription medications, over-the-counter drugs, vitamins, and supplements.
Uses
Advanced renal cell carcinoma Advanced hepatocellular carcinoma Differentiated thyroid carcinoma
How it works
Sorafeb 200mg Tablet 30's works by inhibiting multiple protein kinases involved in tumour cell proliferation and angiogenesis (the formation of new blood vessels that supply tumours). Specifically, it targets receptors for vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and Raf kinases, which play key roles in cancer development and progression. This stops the growth and spread of the tumour cells to other organs, as well as the formation of blood vessels in the tumour cells.
How to Use
The medicine will be prescribed to you by a healthcare professional in a hospital setting. It is not recommended to take this medication with meals that are high in fat since this may reduce Sorafeb 200mg Tablet 30's's effectiveness. Take the pills at least one hour before or two hours after a high-fat meal if you plan to eat one. The dose will be decided by your healthcare professional based on your condition. Avoid crushing, opening, or dissolving the tablet and swallow it whole with a glass of water. Take the Sorafeb 200mg Tablet 30's at the same time every day.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: gastrointestinal perforation abnormal heart rhythm (QT prolongation) Inflammation of the liver breathing or swallowing difficulties Stevens-Johnson Syndrome and toxic epidermal necrolysis Decreased blood flow to the heart Increased risk of bleeding (blood in urine, stool, vomit, cough) Common: Nausea Vomiting Fatigue Diarrhoea Alopecia Hand-foot skin reaction Gut wall bleeding
Expert Tips
Follow all instructions and dosing recommendations provided by your healthcare provider. Do not take more or less of the medication than prescribed. Report any new or worsening symptoms to your healthcare provider immediately, especially if they relate to your lungs, eyes, skin, liver, kidneys, heart, or bleeding. When undergoing this therapy, stay out of direct sunlight and wear sunscreen with an SPF of at least 50 before going outside. Sorafeb 200mg Tablet 30's should not be stopped without first talking to your doctor. Even if you feel better or see a change in your symptoms, you should still talk to your doctor before stopping Sorafeb 200mg Tablets 30's. It is recommended to inform your doctor about other anticancer drugs you have been taking. It's critical to maintain a sufficient fluid intake because dehydration can exacerbate symptoms such as diarrhoea and other gastrointestinal disorders. Remember to attend all scheduled appointments and follow-up visits with your healthcare provider to ensure your treatment is effective and any side effects are managed appropriately.
References
- Bayer (Pty) Ltd, [Revised on 22nd Apr 2016] [Accessed on 15th March 2024], https://www.bayer.com/sites/default/files/NEXAVAR_200_EN_PI.pdf
- Bayer HealthCare Pharmaceuticals Inc., US Food & Drug Administration, [Revised on Dec 2018] [Accessed on 15th March 2024]], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021923s020lbl.pdf
- Bayer AG, European Medicines Compendium (emc), [Revised on April 2023], [Accessed on 15th March 2024], https://www.medicines.org.uk/emc/files/pil.226.pdf
- Zentiva Pharma UK Limited, Medicines Compendium (emc), [Revised on April 2022], [Accessed on 15th March 2024] https://www.medicines.org.uk/emc/files/pil.13098.pdf
- KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
Safety Advice
Pregnancy: unsafe It is not recommended to take Sorafeb 200mg Tablet 30's during pregnancy as it may harm your unborn baby. It is necessary to inform your doctor if you are pregnant or planning to become pregnant.
Lungs: Consult your doctor Consult your doctor if you have any lung diseases before starting the treatment with Sorafeb 200mg Tablet 30's.
Breastfeeding: Consult your doctor It is unknown whether Sorafeb 200mg Tablet 30's passes into the breast milk. It is not recommended to nurse a child during the therapy. This medication might affect your baby's growth and development. Please consult your doctor before breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.