Staurinz 25mg Capsule

Staurinz 25mg capsule contains the active substance midostaurin, a tyrosine kinase inhibitor used as an anti-cancer medicine. In adults with acute myeloid leukaemia (AML) and FLT3 gene mutation, it is used in combination with other chemotherapy medications. Acute myeloid leukaemia is a cancer of myeloid cells, a type of white blood cell, characterised by abnormal overproduction of these cells. The medicine is also indicated in adults for treatment of aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated haematological neoplasm (SM-AHN), or mast cell leukaemia (MCL).

Do not take Staurinz 25mg capsule if you are allergic to midostaurin or any other ingredient in this medicine. Inform your healthcare professional if you have symptoms of infection, heart disorder, lung problems, or breathing difficulties. Report to your doctor immediately if you experience fever, sore throat, mouth ulcers, cough with or without sputum, chest pain, difficulty breathing, or swelling in body parts after taking this medicine.

This medicine is not recommended for children and adolescents below 18 years of age. Before starting therapy, inform your physician if you are pregnant, breastfeeding, or planning pregnancy. Staurinz 25mg capsule may reduce fertility in men and women; discuss this with your doctor before initiating treatment.

The most common side effects of this medicine are fever with reduced blood cell counts, nausea, vomiting, headache, musculoskeletal pain, increased blood glucose levels, and respiratory tract infection.

Acute myeloid leukemia (AML) Aggressive systemic mastocytosis (ASM) Systemic mastocytosis with associated hematological neoplasm (SM-AHN) Mast cell leukemia (MCL)

Staurinz 25mg capsule is a kinase inhibitor that potently inhibits multiple receptor tyrosine kinases. It blocks the action of the kinases in the abnormal cells that express FLT3 mutant genes and stops their division and growth.

Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Take the Staurinz 25mg capsule as prescribed by your doctor. Do not open, break, crush, or chew the capsules. Swallow the capsule whole with a glass of water. Take the capsules with food at the same time each day.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Swelling in the lower limbs Skin rash Increased blood sugar levels Abdominal pain Constipation, diarrhea Nausea, vomiting Musculoskeletal pain Headache Bleeding from nose Upper respiratory infection Tiredness Fever Serious Heart failure GI bleeding Fever with decreased blood cell counts Hypersensitivity reactions Kidney problems Pneumonia Blood infection

Do not breastfeed during the treatment with Staurinz 25mg capsule and for at least 4 months after the last dose. Avoid grapefruit juice during the treatment with this medicine. If you vomit after taking this medicine, do not take another capsule to make up the dose. If you are a male patient with a female partner with reproducing potential, use effective contraception during the treatment and for 4 months after the last dose. Your doctor will perform regular blood tests during the treatment to monitor the number of blood cells and electrolytes in your body. Your heart and lung function will also be checked regularly. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury.