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Stoplos One 5mg Injection

Salt Composition: ZOLEDRONIC ACID

₹984.00₹3171.00

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Stoplos One 5mg Injection contains the active substance zoledronic acid. It belongs to the group of medicines called bisphosphonates. It is used to reduce elevated calcium levels in the blood of adult patients where high calcium occurs due to the presence of a tumour. Tumours can accelerate normal bone turnover in such a way that calcium release from bone is increased. This condition is known as tumour-induced hypercalcaemia (TIH). It is also used to prevent bone complications in adult patients with multiple myeloma and bone metastases from solid tumours (spread of cancer from the primary site to the bone), in addition to standard cancer therapy. Stoplos One 5mg Injection is also indicated to prevent or treat osteoporosis (a condition in which the bones become thin and weak and break easily) in women who have undergone menopause. It is also used to treat osteoporosis in men. It is used to treat Paget's disease of bone (a condition in which the bones are soft and weak and may be deformed, painful, or easily broken). Other uses include treating or preventing osteoporosis in men and women taking glucocorticoids (a corticosteroid medication that may cause osteoporosis). Do not take this injection if you are allergic to zoledronic acid, another bisphosphonate, or any other ingredients of this medicine and if you are pregnant or breastfeeding. Before initiating treatment, inform your doctor if you have kidney or liver problems, bone diseases, pain, swelling, or jaw numbness. This medicine is not recommended for use in adolescents and children below 18 years of age. Zoledronic acid is not cancer chemotherapy and will not slow or stop the spread of cancer. However, it can be used to treat bone diseases in patients with cancer.

Uses

Treat hypercalcemia of malignancy Multiple myeloma Bone metastases from solid tumors Osteoporosis in postmenopausal women Osteoporosis in men Paget’s disease of bone

How it works

Stoplos One 5mg Injection primarily inhibits bone resorption. It works by slowing bone breakdown, increasing bone density (thickness), and decreasing the amount of calcium released from the bones into the blood.

How to Use

It should only be administered by a trained doctor or nurse. It will be given as a drip (infusion) into your vein. Your doctor will decide the dose and duration of the treatment based on your disease severity and other factors. Do not self-administer the medication.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Changes in heart rhythm Severe hypersensitivity skin reactions Decreased calcium levels Severe bone pain Severe kidney problems Unusual fractures of the bone Common Nausea, vomiting Fatigue Anemia Bone pain Constipation, diarrhea dyspnea, and fever Swelling in the legs and feet Decreased weight Abdominal pain Muscle pain Tiredness

Expert Tips

While being treated with Stoplos One 5mg Injection you should maintain good oral hygiene and receive routine dental check-ups. Contact your doctor or dentist immediately if you experience any problems with your mouth or teeth, such as loose teeth, pain or swelling, non-healing sores, or discharge. Inform your physician if you have kidney problems. Your doctor may advise you to take certain blood tests regularly to check the effectiveness of the therapy.

References

  1. Stoplos One 5mg Injection 5 mg solution for infusion - Patient Information Leaflet (PIL) - (emc). www.medicines.org.uk. [revised on 2017] [cited 2023 Mar 28]. Available from: https://www.medicines.org.uk/emc/product/5242/pil
  2. HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use Stoplos One 5mg Injection safely and effectively. See full prescribing information for Stoplos One 5mg Injection. Stoplos One 5mg Injection for intravenous use. [Revised on 2017] [cited 2023 Mar 28]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/203231s011lbl.pdf
  3. KD Tripathi, Hormones and Drugs Affecting Calcium Balance, Essentials of Medical Pharmacology, 8th Edition, 2019, 360-372.

Safety Advice

Pregnancy: unsafe Stoplos One 5mg Injection is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.

Lungs: Consult your doctor It is unknown whether Stoplos One 5mg Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Stoplos One 5mg Injection because the medicine passes into the breast milk in small amounts and may harm your baby.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS