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Suregraft 0.25mg Tablet
Salt Composition: EVEROLIMUS
- Manufacturer: HOSPIMAX HEALTHCARE PVT LTD
- Pack Size: 10 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 0.25MG
- Prescription Required
- Storage: Store Suregraft 0.25mg Tablet in the original package at room temperature (20°C to 25°C). Do not freeze. Keep it out of reach from children.
₹438.00₹547.80
Inclusive of all taxes
Product Introduction
Suregraft 0.25mg Tablet is an antineoplastic drug belonging to the class of mTOR inhibitors, containing the active ingredient everolimus. It is used to treat advanced breast cancer, renal cell carcinoma, pancreatic neuroendocrine tumours, and subependymal giant cell astrocytoma (tumours found in the ventricles of the brain). Good oral hygiene and regular dental check-ups are important during treatment since this medicine can cause sores or ulcers in the mouth. It is often combined with cyclophosphamide, an alkylating agent, for the treatment of subependymal giant cell astrocytoma. Before taking this medicine, it is necessary to know that your risk of bacterial or viral infection increases with this treatment. If you have been infected with Hepatitis B, Suregraft 0.25mg Tablet increases the chances of reinfection. Inform your healthcare provider if you experience fever, chills, cough, yellowing of skin, joint pain or swelling during this treatment. You must limit your exposure to sunlight and UV light by wearing protective clothing and applying sunscreen frequently, as this medicine may increase the risk of developing cancers. Avoid taking grapefruit juice or grapefruit whilst taking this medicine. Suregraft 0.25mg Tablet is not recommended for adolescents and children under the age of 18. Contact your doctor immediately if you experience shortness of breath, chest pain or worsening cough. During Suregraft 0.25mg Tablet treatment, your doctor may periodically monitor your white blood cell counts, platelets, blood sugar, electrolytes and kidney parameters to prevent serious complications. This medicine has the potential to cause kidney problems. Report to your doctor if you have been diagnosed with liver disorders, heart failure, high blood cholesterol levels or hypertension before starting this treatment. Avoid live vaccines and close contact with those who have received live vaccines.
Uses
Advanced breast cancer Advanced renal cell carcinoma Advanced pancreatic neuroendocrine tumours Treatment of subependymal giant cell astrocytoma
How it works
It contains the active ingredient Suregraft 0.25mg Tablet, which inhibits the activity of a protein called mammalian target of rapamycin (mTOR), which regulates cell growth. This drug can slow the growth of abnormal cancer cells by blocking the mTOR protein. Suregraft 0.25mg Tablet helps to reduce the size of tumours and improve outcomes in patients.
How to Use
Your doctor will decide the dose and duration of Suregraft 0.25mg Tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time everyday, with or without food. Do not chew, crush, or break the tablet. Swallow the whole tablet with water. If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Difficulty breathing, or swallowing Swelling of face, lips, tongue, throat Severe itching, red rash, raised bumps Common: Infection (chills, increased temperature) Coughing Wheezing Excessive thirst High urine output or severely decreased urine output Tiredness Bleeding Increased appetite with weight loss
Expert Tips
Suregraft 0.25mg Tablet have the tendency to cause harm to unborn foetus. Inform your healthcare provider before starting this treatment if you are pregnant, or have a partner who can become pregnant. Your health care provider will conduct a pregnancy test before you start treatment with Suregraft 0.25mg Tablet. Discuss effective birth control methods with your healthcare provider and use them during treatment and for 8 weeks after your last dose. It is not known if Suregraft 0.25mg Tablet passes into the breast milk. Hence, it is not recommended to breastfeed during this treatment. Occurrence of mouth ulcers or sores are pretty common during this treatment, so your healthcare provider will prescribe a mouthwash. Use the mouthwash as recommended which helps prevent and manage the symptoms.
References
- Accord Healthcare Limited, Electronic medicines compendium (EMC), [ Revised on Oct 2020] [ Accessed on 18th March 2023], https://www.medicines.org.uk/emc/files/pil.11084.pdf
- Jan Hasskarl; Everolimus; Recent Results in Cancer Research; Published on 2018; Accessed on 18/03/2023; https://pubmed.ncbi.nlm.nih.gov/30069763/
- Novartis Pharmaceuticals Corporation, US Food and Drug Administration, [ Revised on July 2012] [ Accessed on 18th March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022334s016lbl.pdf
- Goodman & Gilmanâs, The Pharmacological Basis of Therapeutics, Targeted therapy: tyrosine kinase inhibitors, monoclonal antibodies, and cytokines, 12th edition, 2011, 1743.
- KD Tripathi, Essentials of Medical Pharmacology, Immunosuppressant drugs, 7th edition, 2013, 878 - 882.
Safety Advice
Pregnancy: unsafe Suregraft 0.25mg Tablet is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Lungs: Consult your doctor It is not known whether Suregraft 0.25mg Tablet can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: Consult your doctor It is not known if Suregraft 0.25mg Tablet passes into your breast milk or if it will affect your baby. Please consult your doctor before breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.