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Sutent 50mg Capsule

Salt Composition: SUNITINIB

₹48802.00₹61003.44

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Sutent 50mg Capsule

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Sutent 50mg Capsule contains the active ingredient sunitinib and belongs to the class of tyrosine kinase inhibitors. It functions by blocking specific tyrosine kinase enzymes that drive the growth and dissemination of cancer cells. This medication is indicated for gastrointestinal stromal tumours (GIST), a rare malignancy that may originate anywhere in the gastrointestinal tract. Sutent 50mg Capsule is also prescribed for advanced renal cancer and pancreatic cancer, particularly pancreatic neuroendocrine tumours (PNET). Cancer develops when abnormal cells multiply without control. This medicine is not recommended for individuals under 18 years of age. Before commencing Sutent 50mg Capsule, manufactured by Pfizer, it is important to discuss your medical history with your doctor, including any history of blood disorders, cardiac problems, hepatic or renal dysfunction, cutaneous disorders, diabetes mellitus, seizure disorders, or thyroid disorders. Inform your physician if you have undergone recent surgery or have planned surgical procedures. Patients with hypertension should exercise caution, as this medication may occasionally elevate blood pressure. Avoid consumption of grapefruit and grapefruit products during treatment with Sutent 50mg Capsule. If you experience oral complications such as pain, swelling, or ulceration, consult your dentist prior to initiating treatment. Patients seeking access or clinical guidance may review the Sutent 50mg Capsule price in India, explore options to purchase Sutent 50mg online in India, or investigate authorised Sutent 50mg patient assistance programme options. Where appropriate, alternative medications such as Sutent 50mg substitutes in India may be considered. Additionally, many patients consult Sutent 50mg reviews to understand the experiences and clinical outcomes of other patients receiving this medication.

Uses

Sutent 50mg uses are: Renal cell carcinoma (RCC) Gastrointestinal stromal tumors (GIST) Pancreatic neuroendocrine tumors (PNET) Medullary thyroid cancer Certain kidney cancer

How it works

The therapeutic effects of Sutent 50mg Capsule include slowing down or stopping the growth and spread of cancer cells in the body, thereby reducing the size and number of tumors. It works by inhibiting the activity of specific proteins known as tyrosine kinases, which are involved in the signaling pathways that control cell growth and division. It can help to prevent cancer cells from growing and spreading by blocking these pathways.

How to Use

Sutent 50mg Capsule is taken orally, in the form of capsules, with a glass of water. The capsules should be swallowed whole and not crushed, chewed, or opened. The recommended dose may vary depending on the type of cancer being treated, the patient's age and weight, and other factors. This medication is usually taken once a day, with or without food, at around the same time each day. If you miss a dose then do not double the dose to compensate for the missed dose .

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Sutent 50mg side effects are as follows: Serious: Heart failure or heart attack Elevated liver function tests. Liver failure Proteinuria Acute kidney injury Interstitial lung disease (inflammation of lung walls) Pulmonary arterial hypertension Gastrointestinal perforation or fistula Haemorrhage (bleeding) Hypothyroidism (low thyroid function) Hypoglycemia (low blood sugar) Common Fatigue Nausea and vomiting Diarrhoea Loss of appetite Hand-foot syndrome Skin discoloration or rash High blood pressure Headache Hair loss Changes in taste Dry skin or itching Nosebleeds

Expert Tips

Follow healthcare provider’s instructions: Take Sutent 50mg Capsule exactly as prescribed by your doctor. Avoid grapefruit: Do not consume grapefruit or grapefruit juice during treatment, as it can increase medication levels in the blood and raise the risk of side effects. Use reliable contraception: Employ a reliable birth control method while taking the medication and for at least four weeks after the last dose. Be aware of side effects: This medication can cause serious side effects, so stay vigilant and monitor your health closely. Report any symptoms: Inform your healthcare provider about any changes in your health, even if they seem minor. Effective cancer treatment: With proper precautions, monitoring, and adherence to instructions, Sutent can be an effective treatment for certain types of cancer.

References

  1. Pfizer, U.S Drug and food safety administration (FDA), [Revised on Dec 2018], [Accessed on 5th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021938s035lbl.pdf
  2. Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.
  3. Robert J. Thomson; Majid Moshirfar; Yasmyne Ronquillo, Tyrosine Kinase Inhibitors, [Revised on 21st Jan 2021] [Accessed on 5th April 2023], https://www.ncbi.nlm.nih.gov/books/NBK563322/
  4. Pfizer, Electronic Medicines Compendium (EMC) [Revised on Mar 2021] [Accessed on 5th April 2023], https://www.medicines.org.uk/emc/files/pil.7966.pdf
  5. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.

Safety Advice

Pregnancy: unsafe Sutent 50mg Capsule is unsafe for a developing fetus and is not recommended during pregnancy as it can cause harm to the developing fetus.

Lungs: unsafe Sutent 50mg Capsules can cause interstitial lung disease (ILD), a serious and potentially fatal condition that causes scarring of the lungs. Patients taking this medication should be monitored for symptoms of ILD, such as cough, shortness of breath, and fever, and treatment should be interrupted or discontinued if necessary.

Breastfeeding: Consult your doctor It is unknown whether Sutent 50mg Capsule is excreted in human breast milk. Breastfeeding women should discuss the potential risks and benefits of the medication with their healthcare provider before starting treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS