Synthivan Tablet

Synthivan tablet is an antiretroviral drug in the protease inhibitors category, containing the active ingredients Atazanavir and Ritonavir. It is used in the treatment of HIV-1 infection. HIV-1 is a virus that attacks and weakens the immune system. This infection progressively weakens immune function, making patients more susceptible to opportunistic infections. The drug is generally not recommended for patients with hepatic impairment because these medications are primarily metabolised in the liver. Hepatic impairment can affect the liver's ability to properly metabolise drugs, leading to potential accumulation in the body and an increased risk of adverse effects. Caution is advised, and alternative treatment options may be considered for patients with hepatic impairment. Your doctor will monitor liver function before and during therapy, particularly in patients with underlying hepatic disease, including hepatitis B and hepatitis C, or marked transaminase elevations. Patients may experience hepatotoxicity when taking this drug. Most patients experience asymptomatic increases in indirect bilirubin, which are reversible upon discontinuation. Do not reduce the dose. If a concomitant transaminase increase occurs, your doctor will evaluate for alternative etiologies. Do not take this drug if you are allergic to Synthivan tablet or other ingredients. During early stages of HIV-1 treatment, some patients may experience an inflammatory response to opportunistic infections. This condition is called immune reconstitution syndrome and can occur after starting this drug or other antiretroviral therapies. Monitoring for signs of worsening infections or inflammatory symptoms is necessary. Inform your healthcare provider if symptoms concern you or persist longer than usual. PR interval prolongation may occur in some patients. Use caution in patients with preexisting conduction system disease or when administered with other drugs that may prolong the PR interval. Patients with advanced HIV may be at increased risk of elevated triglycerides and pancreatitis, a condition caused by inflammation of the pancreas. If you have a history of pancreatitis, you may have a greater chance of it returning during treatment with this drug.

Treatment of HIV-1 infection

Synthivan tablet works together to inhibit the protease enzyme, which is necessary for the replication of HIV. By blocking this enzyme, this drug prevents the virus from multiplying and spreading in the body. It mainly helps reduce the viral load and slow the progression of HIV infection.

Take the Synthivan tablet as advised by your physician. Swallow the tablets whole and intact. This tablet should be taken with food. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the medicine if your doctor advises you to stop.

Side Effects are unwanted symptoms caused by medicines. Although all medicines cause side effects, not everyone gets them. Serious Jaundice Common Nausea, vomiting Diarrhea Abdominal pain Rash Fatigue Neurological disturbances (tingling, numbness, chilling) Headache Fever Depression Insomnia Dizziness Muscle pain

To prevent the spread of HIV-1 infection, avoid sharing needles or syringes, which can transmit HIV-1 infections easily. It's necessary for individuals who use injectable drugs to use sterile needles and syringes and never share them with others. Personal items like toothbrushes, razor blades, or anything with body fluids or blood on them should also be avoided. They should not be shared because HIV-1 can be present in blood and certain body fluids, and sharing these items could mainly transmit the virus. Do not have any sex without protection. It is necessary to practice safe sex using a polyurethane condom or latex to lower the risk of sexual contact with semen, vaginal secretions, or blood. If you must remember to take Synthivan tablet for the entire day, take your usual dose the next day. However, do not double-dose yourself. Do not store this tablet in a moist place like a bathroom cabinet or near the kitchen sink. Keep your tablet in a tightly closed container. Do not accept if the seal over the bottle opening is broken or missing. This medicine was prescribed for your specific condition. Please do not use it for other conditions. Do not give this tablet to other people, even if they have the same symptoms like you have. It may harm them.