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Tacsis Ointment 10gm

Salt Composition: TACROLIMUS

₹317.00₹351.56

Inclusive of all taxes

Tacsis Ointment 10gm

Categories: Nephrology

Conditions: Transplant

Product Introduction

Tacsis Ointment 10gm contains the active ingredient Tacrolimus, an immunosuppressant belonging to the class of calcineurin inhibitors. Tacrolimus ointment 0.1% is used alongside other medicines to prevent organ transplant rejection in patients receiving liver, kidney, heart, or other organ transplants. It works by controlling the body's immune response, enabling acceptance of the transplanted organ. The medicine is also available as a cream formulation.

Do not use Tacsis Ointment if you are allergic to tacrolimus or any other ingredients in this medicine. Inform your doctor if you have an allergy to any antibiotic group. Notify your doctor if you have previously had liver or heart disease before starting treatment.

Seek immediate medical attention if you develop fever, bruising under the skin (appearing as red dots), unexplained tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, or seizures after taking this medicine.

Limit exposure to sunlight and UV light while using tacrolimus by wearing appropriate protective clothing and sunscreen with a high sun protection factor. Monitor for skin changes during immunosuppressive therapy with this medicine.

This medicine may cause diarrhoea; inform your doctor if diarrhoea persists for more than one day. Before receiving any vaccinations, consult your doctor.

Uses

Tacsis Ointment 10gm uses Prevent organ transplant rejections

How it works

Tacsis Ointment 10gm provides immunosuppression by inhibiting T-lymphocyte activation and proliferation and T-helper-cell-dependent B-cell response. It works by attaching to a protein called FKBP-12 and forms a complex called tacrolimus-FKBP, which inhibits the action of calcineurin phosphatase. This, in turn, inhibits the formation of T cells and suppresses the immune response.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Swelling in the arm or leg Hair loss Itchy skin Constipation, diarrhoea Nausea, vomiting Anemia Headache Cough Serious Increased or decreased heartbeats GI bleeding Liver Injury Seizure Acute kidney failure Lung infection or respiratory problems

Expert Tips

Avoid grapefruit and grapefruit juice while using Tacsis Ointment 10gm, as it may affect how the medicine works. Do not consume alcohol during treatment, as it may increase the risk of side effects. Check with your doctor before getting any vaccines, including flu shots, as this medicine may interfere with their effectiveness. Use this medicine as a long-term treatment to prevent organ rejection after a transplant. Do not stop using it without your doctor’s advice. Attend all scheduled medical tests and appointments to help your doctor monitor the treatment's effectiveness and detect any side effects early.

References

  1. Prograf 0.5mg Hard Ointments - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published December 2022. Accessed May 25, 2023. https://www.medicines.org.uk/emc/product/6720/smpc
  2. Highlights Of Prescribing Information, Prograf ® (Tacrolimus) Ointments PROGRAF ® (Tacrolimus) Injection, (for Intravenous Use).; Revised 2012. Accessed May 25, 2023. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/050709s031lbl.pdf
  3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Immunosuppressants, tolerogens, and immunostimulants, 12th edition, 2011, 1008.
  4. KD Tripathi, Essentials of Medical Pharmacology, Immunosuppressant drugs, 7th edition, 2013, 881.

Safety Advice

Pregnancy: Consult Your Doctor Based on animal studies, Tacsis Ointment 10gm can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.

Lungs: Consult Your Doctor It is unknown whether Tacsis Ointment 10gm can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: Unsafe Do not consume Tacsis Ointment 10gm if you are breastfeeding because this medicine is excreted into breast milk and may cause harmful effects on the body.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS