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Taftrio Tablet

Salt Composition: BICTEGRAVIR,EMTRICITABINE,TENOFOVIR ALAFENAMIDE

₹2925.00₹4500.00

Inclusive of all taxes

Taftrio Tablet

Categories: Infectious Disease

Conditions: Antiviral

Product Introduction

Taftrio Tablet is an antiretroviral drug containing Bictegravir, Emtricitabine, and Tenofovir Alafenamide. It is used in the treatment of HIV-1 infection. HIV-1 is a human immunodeficiency virus that attacks and weakens a person's immune system. This infection progressively weakens immunity, making patients more susceptible to opportunistic infections. Do not take this drug if you are allergic to Taftrio Tablet or its ingredients. During the early stages of HIV-1 treatment, some patients may experience an inflammatory response to opportunistic infections, a condition called immune reconstitution syndrome. This can occur after starting this drug or other antiretroviral therapies. Monitor for any signs of worsening infections or inflammatory symptoms and report these to your doctor. Inform your doctor if you have a history of heart failure, pancreatitis, bone disease, fractures, or liver or kidney problems. Patients with pancreatitis or at risk of pancreatitis should take this combination cautiously. During treatment, your doctor may periodically monitor your blood counts, bone mineral density, and liver and kidney parameters to prevent serious complications. Adults of childbearing potential should use effective contraception to prevent unwanted pregnancy. If you are pregnant or think you might be pregnant, your doctor may suggest an alternative treatment, as this combination regimen is not recommended during early pregnancy. Breastfeeding is not recommended due to the possible transmission of HIV-1 infection from mother to baby. Inform your doctor about all your medications, including prescription drugs, over-the-counter medicines, and herbal supplements, to ensure no potential interactions.

Uses

Treatment of Human Immunodeficiency Virus 1 (HIV-1) Infection

How it works

Taftrio Tablet combines integrase strand transfer inhibitors and nucleoside, nucleotide analogue reverse transcriptase inhibitors. It increases the number of CD4 T cells and stimulates the immune system to fight against infections. Thereby, it reduces the viral load of HIV in the blood and decreases the severity of HIV infection.

How to Use

Take the Taftrio Tablet as advised by your physician. Swallow the tablets whole and intact. This tablet should be taken with food. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the medicine if your doctor advises you to stop.

Side Effects

Side Effects are unwanted symptoms caused by medicines. Although all medicines cause side effects, not everyone gets them. Serious Bone loss Worsening of Hepatitis B Kidney injury Immune reconstitution syndrome Lactic acidosis Liver toxicity Common Depression Abnormal dreams Headache Dizziness Diarrhea Feeling sick (Nausea) Tiredness (Fatigue)

Expert Tips

To prevent the spread of HIV-1 infection, avoid sharing needles or syringes, which can transmit HIV-1 infections easily. It's necessary for individuals who use injectable drugs to use sterile needles and syringes and never share them with others. Personal items like toothbrushes, razor blades, or anything with body fluids or blood should also be avoided. They should not be shared because HIV-1 can be present in blood and certain body fluids, and sharing these items could mainly transmit the virus. Do not have any sex without protection. It is necessary to practice safe sex using a polyurethane condom or latex to lower the risk of sexual contact with semen, vaginal secretions, or blood. If you remember to take a Taftrio Tablet for the entire day, take your usual dose the next day. However, do not double-dose yourself. Do not store this tablet in a moist place like a bathroom cabinet or near the kitchen sink. Keep your tablet in a tightly closed container. Do not accept if the seal over the bottle opening is broken or missing. This medicine was prescribed for your specific condition. Please do not use it for other conditions. Do not give this tablet to others, even if they have the same symptoms like you have. It may harm them.

References

  1. Gilead Sciences Inc., U.S. Food and Drug Administration (EMC), [Revised on Oct 2021] [Accessed on 20th May 2023], https://www.medicines.org.uk/emc/files/pil.9313.pdf
  2. KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
  3. Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Antiretroviral agents and treatment of HIV infection, 12th Edition, 2011, 1634-1638.

Safety Advice

Pregnancy: Consult your doctor Consult your physician if you are pregnant or planning for pregnancy during the treatment with Taftrio Tablet.

Lungs: Consult your doctor Whether Taftrio Tablet is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

Breastfeeding: unsafe Breastfeeding is not recommended in individuals taking a Taftrio Tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS