Tasigna 150mg Capsule

Tasigna 150mg capsule is an antineoplastic agent containing nilotinib, a tyrosine kinase inhibitor. It is indicated for treatment of Philadelphia chromosome-positive chronic myeloid leukaemia (Ph-positive CML) in adults and paediatric patients, including those newly diagnosed with chronic myeloid leukaemia and those who have developed intolerance to prior therapy. The medicine is also used in patients with CML who no longer respond to previous treatment, including imatinib.

Do not take this medicine if you are allergic to nilotinib or other ingredients in this formulation. Notify your doctor if you have a history of cardiac conditions including myocardial infarction, abnormal cardiac electrical activity, angina, cerebrovascular accident, or claudication. Inform your doctor if you have hepatic or pancreatic disorder, or deficiency of potassium or magnesium. Disclose all medications you are taking, particularly those used to lower blood cholesterol. Inform your doctor of any prior hepatitis B infection, as this medicine may reactivate hepatitis B, which can be life-threatening in certain cases. Avoid consumption of grapefruit and grapefruit juice. Notify your doctor if you have lactose intolerance, as Tasigna 150mg contains lactose.

During treatment, your doctor may order regular blood tests to monitor hepatic and pancreatic function, and blood cell counts including WBC, RBC, and platelets. Monitoring will also include cardiac function assessment for QT interval prolongation, serum electrolytes, and glucose and lipid levels to evaluate tolerance to Tasigna 150mg. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Use effective contraception during treatment with this medicine.

Blood cancer (Philadelphia chromosome-positive chronic myeloid leukemia) in adults and pediatrics.

BCR-ABL tyrosine kinase is responsible for the uncontrolled division of cells in the CML. Tasigna 150mg disrupts the signaling route of the protein kinase enzyme which targets the BCR-ABL protein and inhibits the growth and spread of cancer cells.

Take Tasigna 150mg as advised by your physician. Swallow the medicine with a glass of water. Do not crush, chew, or open the medicine. Your doctor will decide the correct dose and duration for you based on your age, body weight, and disease condition. Do not stop taking this medicine unless your doctor advises you to stop.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Sudden weight gain Swelling in hands, feet, ankles, or face Chest pain Blood pressure (high and low) Discoloration of tongue, lips, or skin (blue) Abnormal heart (irregular heartbeat) Hair loss Vision problem Stomach pain, vomiting of blood, blood in stools. Yellowing of the skin, eyes, and dark urine. High blood sugar levels. Sensitivity to light Common: Nausea, vomiting, diarrhea. Headache, muscle pain, stomach pain. Hair loss. Tiredness. Constipation. Slowing of growth in children. Pneumonia. Loss of appetite. Sleeplessness, depression, and anxiety. Stomach discomforts like bloating and flatulence after meals musculoskeletal pain

Based on your condition your doctor may prescribe a lower dose. Tasigna 150mg can be used by people aged 65 years and over with the same dose as other adults. Tell your doctor if you experience any irregular heartbeats or any signs of a heart condition because this can lead to serious complications like sudden death. Inform your physician if you have kidney problems. Your physician will decide whether you may receive this medication after monitoring your kidney functions. Some children and adolescents taking this medicine may have slower than normal growth. So, your doctor will regularly monitor your growth. Report to your doctor if you have had a history of heart failure or hepatitis infection. Discuss effective contraceptive options with your healthcare provider.