Tasigna 200mg Capsule

Tasigna 200mg capsule is an antineoplastic medication containing the active ingredient nilotinib. It belongs to the class of tyrosine kinase inhibitors. This medicine is used to treat Philadelphia chromosome-positive chronic myeloid leukaemia (Ph-positive CML), a blood cancer characterised by abnormal white blood cell production. In adult and paediatric patients, it is indicated for newly diagnosed chronic myeloid leukaemia (CML) and for patients experiencing adverse effects from previous treatment. It is also used in patients with CML who no longer respond to prior treatment, including imatinib.

Do not take this medicine if you are allergic to nilotinib or any other ingredients in this formulation. Notify your doctor if you have a current or past history of heart conditions including heart attack, abnormal electrical signals, chest pain, cerebral stroke, or claudication (reduced blood flow in the legs). Inform your doctor if you have liver or pancreatic disease, or if you have hypokalaemia or hypomagnesaemia. Disclose all medications to your doctor, particularly those used to lower blood cholesterol. Inform your doctor about your medical history, especially any prior hepatitis B infection, as this medicine may reactivate hepatitis B, which can be fatal in some cases. Avoid consuming grapefruit or grapefruit juice. Inform your doctor if you have sugar intolerance, as Tasigna 200mg contains lactose.

During treatment, your doctor may order regular blood tests to monitor liver and pancreatic function, and blood cell counts (white blood cells, red blood cells, platelets). Monitoring will also assess heart function through electrocardiography (QT interval prolongation), electrolyte levels, and glucose and lipid concentrations to evaluate tolerability of Tasigna 200mg. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Use effective contraception during treatment with this medicine.

Blood cancer (Philadelphia chromosome-positive chronic myeloid leukemia) in adults and pediatrics.

BCR-ABL tyrosine kinase is responsible for the uncontrolled division of cells in the CML. Tasigna 200mg disrupts the signaling route of the protein kinase enzyme which targets the BCR-ABL protein and inhibits the growth and spread of cancer cells.

Take Tasigna 200mg as advised by your physician. Swallow the medicine with a glass of water. Do not crush, chew, or open the medicine. Your doctor will decide the correct dose and duration for you based on your age, body weight, and disease condition. Do not stop taking Nilotinib unless your doctor advises you to stop.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Sudden weight gain Swelling in hands, feet, ankles, or face Chest pain Blood pressure (high and low) Discoloration of tongue, lips, or skin (blue) Abnormal heart (irregular heartbeat) Hair loss Vision problem Stomach pain, vomiting of blood, blood in stools. Yellowing of the skin, eyes, and dark urine. High blood sugar levels. Sensitivity to light Common: Nausea, vomiting, diarrhea. Headache, muscle pain, stomach pain. Hair loss. Tiredness. Constipation. Slowing of growth in children. Pneumonia. Loss of appetite. Sleeplessness, depression, and anxiety. Stomach discomforts like bloating and flatulence after meals musculoskeletal pain

Based on your condition your doctor may prescribe a lower dose. Tasigna 200mg can be used by people aged 65 years and over with the same dose as other adults. Tell your doctor if you experience any irregular heartbeats or any signs of a heart condition because this can lead to serious complications like sudden death. Inform your physician if you have kidney problems. Your physician will decide whether you may receive this medication after monitoring your kidney functions. Some children and adolescents taking this medicine may have slower than normal growth. So, your doctor will regularly monitor your growth. Report to your doctor if you have had a history of heart failure or hepatitis infection. Discuss effective contraceptive options with your healthcare provider.